Detailed information NTG1131345

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: H1X63_RS04900
• Genome accession: NZ_LR822027
• Coordinates: 932317..934464 (-)
• Length: 715 a.a.
• NCBI ID: WP_179972943.1
• Uniprot ID: A0A8D6U738
• Organism: Streptococcus thermophilus isolate STH_CIRM_998
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 927317..939464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X63_RS04880 (STHERMO_1041)	cas1	928254..929258 (+)	1005	WP_014621545.1	CRISPR-associated endonuclease Cas1	-
H1X63_RS04885 (STHERMO_1042)	cas2	929258..929587 (+)	330	WP_014608281.1	CRISPR-associated endonuclease Cas2	-
H1X63_RS04890 (STHERMO_1044)	-	930454..930876 (+)	423	WP_095559351.1	ribosomal RNA small subunit methyltransferase A	-
H1X63_RS11085	-	930911..932305 (-)	1395	Protein_915	bacteriocin secretion accessory protein	-
H1X63_RS04900 (STHERMO_1047)	comA/nlmT	932317..934464 (-)	2148	WP_179972943.1	peptide cleavage/export ABC transporter	Regulator
H1X63_RS04905 (STHERMO_1048)	-	934739..934960 (+)	222	WP_101415610.1	Blp family class II bacteriocin	-
H1X63_RS04910 (STHERMO_1049)	-	935012..935239 (+)	228	WP_058621356.1	bacteriocin class II family protein	-
H1X63_RS04915 (STHERMO_1050)	-	935261..935644 (+)	384	WP_095559354.1	hypothetical protein	-
H1X63_RS04920	-	935641..935844 (+)	204	Protein_920	garvicin Q family class II bacteriocin	-
H1X63_RS04925 (STHERMO_1051)	-	935856..936158 (+)	303	WP_015695689.1	bacteriocin immunity protein	-
H1X63_RS04930 (STHERMO_1052)	-	936316..936549 (+)	234	WP_179972944.1	Blp family class II bacteriocin	-
H1X63_RS04935 (STHERMO_1053)	-	936739..936996 (+)	258	WP_095559356.1	garvicin Q family class II bacteriocin	-
H1X63_RS04940 (STHERMO_1054)	-	936996..937304 (+)	309	WP_018364976.1	bacteriocin immunity protein	-
H1X63_RS04945 (STHERMO_1055)	-	937679..937858 (+)	180	WP_095559357.1	hypothetical protein	-
H1X63_RS04950 (STHERMO_1056)	-	938101..938301 (+)	201	WP_006531882.1	bacteriocin class II family protein	-
H1X63_RS04955 (STHERMO_1057)	-	938327..938509 (+)	183	WP_006531883.1	Blp family class II bacteriocin	-
H1X63_RS04960 (STHERMO_1058)	-	939126..939356 (+)	231	WP_043878356.1	bacteriocin	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80091.92 Da
• Isoelectric Point: 7.1853

>NTDB_id=1131345 H1X63_RS04900 WP_179972943.1 932317..934464(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_998]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMPKERFEKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNHLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNANLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVAILWYGSHLVMAGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFNGKQLLNDSHFLQG
DIVFDDVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIELMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGQVIEEGHHKQLIQNQGFYAQLFHE

Nucleotide

• Length: 2148 bp

>NTDB_id=1131345 H1X63_RS04900 WP_179972943.1 932317..934464(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGAGGAGATACAAGTATGTTAGTCAGATTGATTTGCGAGATTGTGGTGTGGCAGCTTTGGCGTCAGTTGCCAAGCATTA
TGGATCTGATTTCTCACTGGCACACCTAAGGGAATTAGCTAAAACAACTAAGGAAGGGACGACAGCGTTAGGGATAGTCG
AGGCAGCTAAAGCCATTGGCTTTGAAACACGCGCCATTCAAGCTAACATGGAACTGTTTGATATGGCCGATATTCCCTAT
CCTTTTATTGTTCATGTTAACAAAGAAGGCAAACTGCAGCACTATTATGTCGTTTACAAAGCTAAGAAAAACCACCTTAT
CATCGGTGATCCAGACCCCAGTGTCAAAGTGACCAAAATGCCCAAGGAGCGCTTTGAAAAGGAATGGACAGGTGTCGCCA
TTTTCTTAGCACCTGCTCCGCATTATCAACCGCATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAACATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCATTTGCAATCCACTCTTGGCATTGTCTCGGTTGGGTTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCACATTTTTGAATTGCCCATGTCTTTTTTTGCCACAAGGCGGACAGGTGAAGTGATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATGCCAATCTCTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGTGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTAATTTTA
AACGTCGCTATTCTCTGGTATGGTTCACATTTAGTCATGGCTGGGAACATTTCAGTAGGTCAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACACCAATGGAAAATATTATTAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAACA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTAATGGCAAACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTTTTTGATGATGTTTCTTATAAATATGGTTTTGGTCGTGACACGCTGAGTCATGTGAATTTACACATTAAGAA
AGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGTTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGCCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACGATTTTAGAAAATTTAACCTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATTGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGGTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
AACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACAAGTTA
TCGAAGAAGGGCATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

• ABC transporter (ABC_tran) (498-647)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.827	99.72	0.706
comA	Streptococcus mitis NCTC 12261	67.465	99.301	0.67
comA	Streptococcus pneumoniae D39	67.232	99.021	0.666
comA	Streptococcus pneumoniae R6	67.232	99.021	0.666
comA	Streptococcus pneumoniae Rx1	67.232	99.021	0.666
comA	Streptococcus mitis SK321	66.901	99.301	0.664
comA	Streptococcus gordonii str. Challis substr. CH1	66.48	99.72	0.663
comA	Streptococcus pneumoniae TIGR4	66.949	99.021	0.663