Detailed information NTG1131284

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H1W98_RS05655
• Genome accession: NZ_LR822026
• Coordinates: 1073992..1074699 (-)
• Length: 235 a.a.
• NCBI ID: WP_179971935.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_967
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1068992..1079699

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W98_RS05630 (STHERMO_1268)	yidA	1069342..1070151 (+)	810	WP_179971931.1	sugar-phosphatase	-
H1W98_RS05635 (STHERMO_1269)	-	1070153..1071367 (+)	1215	WP_179973777.1	aminoacyltransferase	-
H1W98_RS05640 (STHERMO_1270)	-	1071420..1071781 (-)	362	Protein_1058	YbaN family protein	-
H1W98_RS05645 (STHERMO_1271)	vicX	1071841..1072653 (-)	813	WP_179971933.1	MBL fold metallo-hydrolase	Regulator
H1W98_RS05650 (STHERMO_1272)	vicK	1072659..1073999 (-)	1341	WP_179971934.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H1W98_RS05655 (STHERMO_1273)	vicR	1073992..1074699 (-)	708	WP_179971935.1	response regulator YycF	Regulator
H1W98_RS05660 (STHERMO_1275)	-	1075223..1075990 (+)	768	WP_180482604.1	amino acid ABC transporter ATP-binding protein	-
H1W98_RS05665 (STHERMO_1276)	-	1076002..1076835 (+)	834	WP_180482603.1	transporter substrate-binding domain-containing protein	-
H1W98_RS05670 (STHERMO_1277)	-	1076853..1077551 (+)	699	WP_179971938.1	amino acid ABC transporter permease	-
H1W98_RS05675 (STHERMO_1278)	-	1077563..1078213 (+)	651	WP_179971939.1	amino acid ABC transporter permease	-
H1W98_RS05680 (STHERMO_1280)	-	1078277..1079533 (-)	1257	WP_180483860.1	ISL3 family transposase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27205.13 Da
• Isoelectric Point: 4.8347

>NTDB_id=1131284 H1W98_RS05655 WP_179971935.1 1073992..1074699(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_967]
MKKILVVDDERPISDIIKFNLTKEGYEVVTTFDGREALEQFEAEKPDLVILDLMLPELDGLEVVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEDNSNFGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1131284 H1W98_RS05655 WP_179971935.1 1073992..1074699(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_967]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGACCTTTGATGGTCGTGAAGCTTTGGAACAATTTGAAGCTGAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGTCAAGGAAATCCGTAAAACGAGCCACACACCAATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTAACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACAATTGAAACTGCAGTAGAAGATAACTCTAACTTTGGCA
AGCAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAGATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	84.255	100	0.843
micA	Streptococcus pneumoniae Cp1015	78.97	99.149	0.783
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
covR	Streptococcus salivarius strain HSISS4	44.444	99.574	0.443
scnR	Streptococcus mutans UA159	38.983	100	0.391