Detailed information NTG1131248

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H1X08_RS10405
• Genome accession: NZ_LR822025
• Coordinates: 2017275..2018510 (+)
• Length: 411 a.a.
• NCBI ID: WP_180482326.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_961
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2012275..2023510

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X08_RS10375 (STHERMO_2377)	-	2012742..2015348 (+)	2607	WP_180482325.1	YfhO family protein	-
H1X08_RS10395 (STHERMO_2378)	-	2015892..2016575 (-)	684	WP_179972452.1	YoaK family protein	-
H1X08_RS10400 (STHERMO_2379)	rlmH	2016591..2017070 (-)	480	WP_180482678.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H1X08_RS10405 (STHERMO_2380)	htrA	2017275..2018510 (+)	1236	WP_180482326.1	S1C family serine protease	Regulator
H1X08_RS10410 (STHERMO_2381)	spo0J	2018576..2019343 (+)	768	WP_084826210.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 43001.32 Da
• Isoelectric Point: 4.7051

>NTDB_id=1131248 H1X08_RS10405 WP_180482326.1 2017275..2018510(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_961]
MKKFNWKKIIEPIAMLVIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYDHIFGGGDSSDSSQENSKDSDGLQVASEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEIAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAVQT
DAAINPGNSGGPLVNIEGQVIGINSSKISSTSAVAGSPVEGIGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSAISKLNLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDI
KLTKSTKDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1131248 H1X08_RS10405 WP_180482326.1 2017275..2018510(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGAAAAAATTTAACTGGAAAAAAATAATAGAGCCAATTGCAATGCTAGTTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACAGGAGTAAAGACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTGAATGACCTATATGACCATATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTAGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATTATGCTTTCGGATGGTTCAAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTGGGTGAAATAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACAATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTGTCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTCCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTCCCGTTGAGGGTATAGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGTAGCGCAATTTCTAAATTAAATTTACCAGATGAAGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACCGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACAGTAGATATT
AAATTAACAAAATCTACAAAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (46-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.042	98.054	0.599
htrA	Streptococcus gordonii str. Challis substr. CH1	57.282	100	0.574
htrA	Streptococcus mitis NCTC 12261	54.523	99.513	0.543
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54