Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   H1X08_RS05330 Genome accession   NZ_LR822025
Coordinates   1038150..1040297 (+) Length   715 a.a.
NCBI ID   WP_095559353.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_961     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1033150..1045297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X08_RS05270 (STHERMO_1191) - 1033452..1033856 (-) 405 WP_015695682.1 hypothetical protein -
  H1X08_RS05275 - 1033914..1034006 (-) 93 Protein_998 Blp family class II bacteriocin -
  H1X08_RS05280 (STHERMO_1192) - 1034220..1034531 (-) 312 WP_003066586.1 hypothetical protein -
  H1X08_RS05285 (STHERMO_1193) - 1034620..1034850 (-) 231 WP_043878356.1 bacteriocin -
  H1X08_RS05290 (STHERMO_1195) - 1035467..1035649 (-) 183 WP_180481989.1 Blp family class II bacteriocin -
  H1X08_RS05295 (STHERMO_1196) - 1035675..1035875 (-) 201 WP_006531882.1 bacteriocin class II family protein -
  H1X08_RS05300 (STHERMO_1198) - 1036065..1036298 (-) 234 WP_095559355.1 Blp family class II bacteriocin -
  H1X08_RS05305 (STHERMO_1199) - 1036456..1036758 (-) 303 WP_015695689.1 bacteriocin immunity protein -
  H1X08_RS05310 - 1036770..1036973 (-) 204 Protein_1005 garvicin Q family class II bacteriocin -
  H1X08_RS05315 (STHERMO_1201) - 1036970..1037353 (-) 384 WP_018364971.1 hypothetical protein -
  H1X08_RS05320 (STHERMO_1202) - 1037375..1037602 (-) 228 WP_058621356.1 bacteriocin class II family protein -
  H1X08_RS05325 (STHERMO_1203) - 1037654..1037875 (-) 222 WP_101415610.1 Blp family class II bacteriocin -
  H1X08_RS05330 (STHERMO_1204) comA/nlmT 1038150..1040297 (+) 2148 WP_095559353.1 peptide cleavage/export ABC transporter Regulator
  H1X08_RS05335 (STHERMO_1205) - 1040309..1041703 (+) 1395 WP_095559352.1 bacteriocin secretion accessory protein -
  H1X08_RS05340 (STHERMO_1206) - 1041738..1042163 (-) 426 Protein_1011 ribosomal RNA small subunit methyltransferase A -
  H1X08_RS05345 (STHERMO_1207) cas2 1042515..1042844 (-) 330 WP_014608281.1 CRISPR-associated endonuclease Cas2 -
  H1X08_RS05350 (STHERMO_1208) cas1 1042844..1043848 (-) 1005 WP_014621545.1 CRISPR-associated endonuclease Cas1 -
  H1X08_RS05355 (STHERMO_1209) - 1043987..1044943 (-) 957 WP_179973117.1 dihydroorotate dehydrogenase -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 80092.91 Da        Isoelectric Point: 7.0609

>NTDB_id=1131211 H1X08_RS05330 WP_095559353.1 1038150..1040297(+) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_961]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMPKERFEKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNHLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNANLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVAILWYGSHLVMAGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDGKQLLNDSHFLQG
DIVFDDVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIELMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGQVIEEGHHKQLIQNQGFYAQLFHE

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=1131211 H1X08_RS05330 WP_095559353.1 1038150..1040297(+) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGAGGAGATACAAGTATGTTAGTCAGATTGATTTGCGAGATTGTGGTGTGGCAGCTTTGGCGTCAGTTGCCAAGCATTA
TGGATCTGATTTCTCACTGGCACACCTAAGGGAATTAGCTAAAACAACTAAGGAAGGGACGACAGCGTTAGGGATAGTCG
AGGCAGCTAAAGCCATTGGCTTTGAAACACGCGCCATTCAAGCTAACATGGAACTGTTTGATATGGCCGATATTCCCTAT
CCTTTTATTGTTCATGTTAACAAAGAAGGCAAACTGCAGCACTATTATGTCGTTTACAAAGCTAAGAAAAACCACCTTAT
CATCGGTGATCCAGACCCCAGTGTCAAAGTGACCAAAATGCCCAAGGAGCGCTTTGAAAAGGAATGGACAGGTGTCGCCA
TTTTCTTAGCACCTGCTCCGCATTATCAACCGCATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAACATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCATTTGCAATCCACTCTTGGCATTGTCTCGGTTGGGTTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCACATTTTTGAATTGCCCATGTCTTTTTTTGCCACAAGGCGGACAGGTGAAGTGATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATGCCAATCTCTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGTGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTAATTTTA
AACGTCGCTATTCTCTGGTATGGTTCACATTTAGTCATGGCTGGGAACATTTCAGTAGGTCAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACACCAATGGAAAATATTATTAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAACA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTGATGGCAAACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTTTTTGATGATGTTTCTTATAAATATGGTTTTGGTCGTGACACGCTGAGTCATGTGAATTTACACATTAAGAA
AGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGTTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGCCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACGATTTTAGAAAATTTAACCTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATTGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGGTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
AACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACAAGTTA
TCGAAGAAGGGCATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-140)

ABC transporter transmembrane region (ABC_membrane)

(166-436)

ABC transporter (ABC_tran)

(498-647)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.827

99.72

0.706
  comA Streptococcus mitis NCTC 12261

67.465

99.301

0.67
  comA Streptococcus pneumoniae D39

67.232

99.021

0.666
  comA Streptococcus pneumoniae R6

67.232

99.021

0.666
  comA Streptococcus pneumoniae Rx1

67.232

99.021

0.666
  comA Streptococcus mitis SK321

66.901

99.301

0.664
  comA Streptococcus gordonii str. Challis substr. CH1

66.48

99.72

0.663
  comA Streptococcus pneumoniae TIGR4

66.949

99.021

0.663

Multiple sequence alignment