Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H0513_RS01930 Genome accession   NZ_LR822023
Coordinates   350032..350721 (+) Length   229 a.a.
NCBI ID   WP_179972618.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_368     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 345032..355721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0513_RS10780 (STHERMO_0379) - 345996..346147 (+) 152 Protein_318 ascorbate 6-phosphate lactonase -
  H0513_RS01910 (STHERMO_0380) - 346185..346856 (-) 672 WP_100284858.1 potassium channel family protein -
  H0513_RS01915 (STHERMO_0381) - 346896..348260 (-) 1365 WP_100284859.1 TrkH family potassium uptake protein -
  H0513_RS01920 (STHERMO_0382) rsmG 348330..349043 (-) 714 WP_179972617.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H0513_RS01925 (STHERMO_0383) - 349340..349876 (+) 537 WP_179972978.1 DUF177 domain-containing protein -
  H0513_RS01930 (STHERMO_0384) covR 350032..350721 (+) 690 WP_179972618.1 response regulator transcription factor Regulator
  H0513_RS01935 (STHERMO_0385) covS 350718..352235 (+) 1518 WP_179972619.1 HAMP domain-containing histidine kinase Regulator
  H0513_RS01940 (STHERMO_0386) nrdR 352357..352836 (+) 480 WP_179972620.1 transcriptional regulator NrdR -
  H0513_RS01945 (STHERMO_0387) - 352833..354008 (+) 1176 WP_179972621.1 DnaD domain protein -
  H0513_RS01950 (STHERMO_0388) dnaI 354012..354914 (+) 903 WP_179972622.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26582.76 Da        Isoelectric Point: 4.9548

>NTDB_id=1131135 H0513_RS01930 WP_179972618.1 350032..350721(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_368]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIKATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRGR

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1131135 H0513_RS01930 WP_179972618.1 350032..350721(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_368]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGATGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCAAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGGAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

96.035

99.127

0.952
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

45.064

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment