Detailed information NTG1131136

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: H0513_RS01935
• Genome accession: NZ_LR822023
• Coordinates: 350718..352235 (+)
• Length: 505 a.a.
• NCBI ID: WP_179972619.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_368
• Function: repress comR expression (predicted from homology) Competence regulation

Genomic Context

Location: 345718..357235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0513_RS10780 (STHERMO_0379)	-	345996..346147 (+)	152	Protein_318	ascorbate 6-phosphate lactonase	-
H0513_RS01910 (STHERMO_0380)	-	346185..346856 (-)	672	WP_100284858.1	potassium channel family protein	-
H0513_RS01915 (STHERMO_0381)	-	346896..348260 (-)	1365	WP_100284859.1	TrkH family potassium uptake protein	-
H0513_RS01920 (STHERMO_0382)	rsmG	348330..349043 (-)	714	WP_179972617.1	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	-
H0513_RS01925 (STHERMO_0383)	-	349340..349876 (+)	537	WP_179972978.1	DUF177 domain-containing protein	-
H0513_RS01930 (STHERMO_0384)	covR	350032..350721 (+)	690	WP_179972618.1	response regulator transcription factor	Regulator
H0513_RS01935 (STHERMO_0385)	covS	350718..352235 (+)	1518	WP_179972619.1	HAMP domain-containing histidine kinase	Regulator
H0513_RS01940 (STHERMO_0386)	nrdR	352357..352836 (+)	480	WP_179972620.1	transcriptional regulator NrdR	-
H0513_RS01945 (STHERMO_0387)	-	352833..354008 (+)	1176	WP_179972621.1	DnaD domain protein	-
H0513_RS01950 (STHERMO_0388)	dnaI	354012..354914 (+)	903	WP_179972622.1	primosomal protein DnaI	-
H0513_RS01955 (STHERMO_0389)	der	355020..356330 (+)	1311	WP_100284866.1	ribosome biogenesis GTPase Der	-
H0513_RS01960	-	356394..357062 (+)	669	Protein_329	HI_0552 family protein	-

Sequence

Protein

• Length: 505 a.a.
• Molecular weight: 57469.79 Da
• Isoelectric Point: 5.0789

>NTDB_id=1131136 H0513_RS01935 WP_179972619.1 350718..352235(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_368]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYSSIINGVLSEKRSLDGQVAVSNKLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKNTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTIVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIGSHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSESLDRPAQIYSQHFEQVITILIDNAVKY
SPVNKEIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFADSETTTPQLEG

Nucleotide

• Length: 1518 bp

>NTDB_id=1131136 H0513_RS01935 WP_179972619.1 350718..352235(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_368]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTAGCGGCCCTCTAT
TCACCGAAAAATATCTATTCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAAATTATATTCTAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGTATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAATACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTCTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTATAGTTGTTTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGGGAGTCATGATGAGATTGGTGCTTTGGCGCTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCTATTGCAGTTATTAAGGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGA
GTTTAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGGAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATCTTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGACTCAGAAACTACGACACCTCAACTTGAAGGTTAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (213-265)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (384-493)

• His Kinase A (phospho-acceptor) domain (HisKA) (270-329)

• ArlS sensor domain (ArlS_N) (39-187)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Streptococcus salivarius strain HSISS4	94.821	99.406	0.943