Detailed information NTG1131120

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H0514_RS10350
• Genome accession: NZ_LR822020
• Coordinates: 1996702..1997937 (+)
• Length: 411 a.a.
• NCBI ID: WP_179973243.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1991702..2002937

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS10320 (STHERMO_2356)	-	1992169..1994775 (+)	2607	WP_179972451.1	YfhO family protein	-
H0514_RS10340 (STHERMO_2357)	-	1995319..1996002 (-)	684	WP_179972452.1	YoaK family protein	-
H0514_RS10345 (STHERMO_2358)	rlmH	1996018..1996497 (-)	480	WP_084826208.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H0514_RS10350 (STHERMO_2359)	htrA	1996702..1997937 (+)	1236	WP_179973243.1	S1C family serine protease	Regulator
H0514_RS10355 (STHERMO_2360)	spo0J	1998003..1998770 (+)	768	WP_084826210.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42975.28 Da
• Isoelectric Point: 4.7051

>NTDB_id=1131120 H0514_RS10350 WP_179973243.1 1996702..1997937(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_956]
MKKFNWKKIIEPIAMLVIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYDHIFGGGDSSDSSQENSKDSDGLQVASEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEIAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAVQT
DAAINPGNSGGPLVNIEGQVIGINSSKISSTSAVAGSAVEGIGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSAISKLNLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDI
KLTKSTKDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1131120 H0514_RS10350 WP_179973243.1 1996702..1997937(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGAAAAAATTTAACTGGAAAAAAATAATAGAGCCAATTGCAATGCTAGTTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACAGGAGTAAAGACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTGAATGACCTATATGACCATATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTAGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATTATGCTTTCGGATGGTTCAAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTGGGTGAAATAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACAATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTGTCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTCCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCCGTTGAGGGTATAGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGTAGCGCAATTTCTAAATTAAATTTACCAGATGAAGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACCGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACAGTAGATATT
AAATTAACAAAATCTACAAAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (14-406)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.29	98.054	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	57.282	100	0.574
htrA	Streptococcus mitis NCTC 12261	54.523	99.513	0.543
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54