Detailed information NTG1131079

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H0514_RS02495
• Genome accession: NZ_LR822020
• Coordinates: 470852..473092 (+)
• Length: 746 a.a.
• NCBI ID: WP_179972172.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 465852..478092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS02470 (STHERMO_0556)	-	467179..467448 (-)	270	WP_179972176.1	GIY-YIG nuclease family protein	-
H0514_RS02475 (STHERMO_0557)	-	467452..468216 (-)	765	WP_179972175.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H0514_RS11120	-	468266..469176 (-)	911	Protein_447	polysaccharide deacetylase family protein	-
H0514_RS02485 (STHERMO_0560)	-	469306..470061 (+)	756	WP_179972174.1	lysophospholipid acyltransferase family protein	-
H0514_RS02490 (STHERMO_0561)	comEA	470167..470862 (+)	696	WP_179972173.1	helix-hairpin-helix domain-containing protein	Machinery gene
H0514_RS02495 (STHERMO_0562)	comEC/celB	470852..473092 (+)	2241	WP_179972172.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H0514_RS02500 (STHERMO_0563)	-	473178..474440 (+)	1263	WP_179972171.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0514_RS02505	-	474506..475051 (+)	546	Protein_452	GNAT family N-acetyltransferase	-
H0514_RS02510 (STHERMO_0566)	spxR	475044..476324 (+)	1281	WP_179972170.1	CBS-HotDog domain-containing transcription factor SpxR	-
H0514_RS02515 (STHERMO_0567)	-	476368..477228 (+)	861	WP_002951571.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84981.00 Da
• Isoelectric Point: 9.9593

>NTDB_id=1131079 H0514_RS02495 WP_179972172.1 470852..473092(+) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_956]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYNIAIMQDKQ
APAEIHQVTLVADTLSVNGERLSAIGKSNGQTYRVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIERLEHVVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNPLFEWMEFFLTWIQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFVSKEKWQEGSQTSNAEKTLIPYLQERGVSQIDYLVLTHTDT
DHIGDLEEVAKRFKIKEICVSKGALTKPSFAKRIRFLKRPVRTLKAGDKLTMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMASYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDLDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1131079 H0514_RS02495 WP_179972172.1 470852..473092(+) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACAATATAGCTATCATGCAAGATAAACAA
GCTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCGGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACGAGTCAAA
CGCTTGTTTTAAAAGGAAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGTCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAATCCACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GATACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
GACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGTCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATTTACAGGAAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GATCATATTGGTGATTTGGAGGAAGTGGCTAAACGGTTTAAGATTAAGGAAATTTGTGTCAGTAAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAACGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGACTATGATGG
GAAGTAACCTACAGGTTCTTTATCCTAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTTTGTTTACTGGTGATTTAGAAAAAGAAGGAGAGGAGGAATTAATGGCTAGCTATCCAAATTTAAA
AGTAAGGGTCCTAAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCTGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCTGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus mitis SK321	46.791	100	0.469
comEC/celB	Streptococcus pneumoniae TIGR4	46.123	100	0.462
comEC/celB	Streptococcus pneumoniae Rx1	45.856	100	0.46
comEC/celB	Streptococcus pneumoniae D39	45.856	100	0.46
comEC/celB	Streptococcus pneumoniae R6	45.856	100	0.46
comEC	Lactococcus lactis subsp. cremoris KW2	44.69	97.185	0.434