Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H0514_RS02490 Genome accession   NZ_LR822020
Coordinates   470167..470862 (+) Length   231 a.a.
NCBI ID   WP_179972173.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 465167..475862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS02470 (STHERMO_0556) - 467179..467448 (-) 270 WP_179972176.1 GIY-YIG nuclease family protein -
  H0514_RS02475 (STHERMO_0557) - 467452..468216 (-) 765 WP_179972175.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H0514_RS11120 - 468266..469176 (-) 911 Protein_447 polysaccharide deacetylase family protein -
  H0514_RS02485 (STHERMO_0560) - 469306..470061 (+) 756 WP_179972174.1 lysophospholipid acyltransferase family protein -
  H0514_RS02490 (STHERMO_0561) comEA 470167..470862 (+) 696 WP_179972173.1 helix-hairpin-helix domain-containing protein Machinery gene
  H0514_RS02495 (STHERMO_0562) comEC/celB 470852..473092 (+) 2241 WP_179972172.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  H0514_RS02500 (STHERMO_0563) - 473178..474440 (+) 1263 WP_179972171.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H0514_RS02505 - 474506..475051 (+) 546 Protein_452 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24480.45 Da        Isoelectric Point: 4.6300

>NTDB_id=1131078 H0514_RS02490 WP_179972173.1 470167..470862(+) (comEA) [Streptococcus thermophilus isolate STH_CIRM_956]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALPTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRAEDVIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1131078 H0514_RS02490 WP_179972173.1 470167..470862(+) (comEA) [Streptococcus thermophilus isolate STH_CIRM_956]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGCCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTATCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGGCAGAGGATGTCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

99.567

100

0.996
  comEA/celA/cilE Streptococcus mitis SK321

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385

Multiple sequence alignment