Detailed information NTG1131073

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: H0514_RS01860
• Genome accession: NZ_LR822020
• Coordinates: 351298..353451 (+)
• Length: 717 a.a.
• NCBI ID: WP_133264081.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 346298..358451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS10535 (STHERMO_0400)	-	346537..346740 (+)	204	WP_232086250.1	hypothetical protein	-
H0514_RS01850 (STHERMO_0401)	-	346789..348546 (+)	1758	WP_179972245.1	ABC transporter ATP-binding protein	-
H0514_RS01855 (STHERMO_0402)	-	348539..350284 (+)	1746	WP_179973259.1	ABC transporter ATP-binding protein	-
H0514_RS01860 (STHERMO_0407)	comA/nlmT	351298..353451 (+)	2154	WP_133264081.1	peptide cleavage/export ABC transporter	Regulator
H0514_RS01865 (STHERMO_0408)	-	353467..354834 (+)	1368	WP_096811636.1	bacteriocin secretion accessory protein	-
H0514_RS01870 (STHERMO_0409)	-	354849..355010 (+)	162	WP_011226496.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
H0514_RS10540	-	355028..355831 (-)	804	WP_232086251.1	ATP-binding protein	-
H0514_RS01880 (STHERMO_0411)	-	356362..357099 (-)	738	WP_179972243.1	LytR/AlgR family response regulator transcription factor	-
H0514_RS01885 (STHERMO_0412)	-	357350..357526 (+)	177	WP_011681570.1	Blp family class II bacteriocin	-
H0514_RS01890 (STHERMO_0413)	-	357545..357745 (+)	201	WP_011681569.1	hypothetical protein	-
H0514_RS01895 (STHERMO_0414)	-	358101..358331 (+)	231	WP_011226494.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80601.42 Da
• Isoelectric Point: 6.8332

>NTDB_id=1131073 H0514_RS01860 WP_133264081.1 351298..353451(+) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_956]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGITLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFVDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDQGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=1131073 H0514_RS01860 WP_133264081.1 351298..353451(+) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTA
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTGACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTGTTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTAAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCAGGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	68.207	99.582	0.679
comA	Streptococcus mitis NCTC 12261	66.385	99.163	0.658
comA	Streptococcus pneumoniae Rx1	65.963	99.163	0.654
comA	Streptococcus pneumoniae D39	65.963	99.163	0.654
comA	Streptococcus pneumoniae R6	65.963	99.163	0.654
comA	Streptococcus mitis SK321	65.682	99.163	0.651
comA	Streptococcus pneumoniae TIGR4	65.541	99.163	0.65
comA	Streptococcus gordonii str. Challis substr. CH1	64.566	99.582	0.643