Detailed information NTG1130938

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H0506_RS09310
• Genome accession: NZ_LR822015
• Coordinates: 1785982..1787217 (+)
• Length: 411 a.a.
• NCBI ID: WP_011226713.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_65
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1780982..1792217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0506_RS09280 (STHERMO_2063)	-	1781448..1784054 (+)	2607	WP_011226710.1	YfhO family protein	-
H0506_RS09300 (STHERMO_2064)	-	1784599..1785282 (-)	684	WP_011226711.1	YoaK family protein	-
H0506_RS09305 (STHERMO_2065)	rlmH	1785298..1785777 (-)	480	WP_011226712.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H0506_RS09310 (STHERMO_2066)	htrA	1785982..1787217 (+)	1236	WP_011226713.1	S1C family serine protease	Regulator
H0506_RS09315 (STHERMO_2067)	spo0J	1787283..1788050 (+)	768	WP_011226714.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42859.14 Da
• Isoelectric Point: 4.7061

>NTDB_id=1130938 H0506_RS09310 WP_011226713.1 1785982..1787217(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_65]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1130938 H0506_RS09310 WP_011226713.1 1785982..1787217(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_65]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCATGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGAATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (4-406)

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.282	100	0.574
htrA	Streptococcus mitis NCTC 12261	53.79	99.513	0.535
htrA	Streptococcus pneumoniae TIGR4	53.545	99.513	0.533
htrA	Streptococcus pneumoniae D39	53.545	99.513	0.533
htrA	Streptococcus pneumoniae Rx1	53.545	99.513	0.533
htrA	Streptococcus pneumoniae R6	53.545	99.513	0.533