Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H0508_RS08465 Genome accession   NZ_LR822014
Coordinates   1642956..1644056 (-) Length   366 a.a.
NCBI ID   WP_148148900.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_36     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1637956..1649056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0508_RS08425 (STHERMO_1891) - 1638568..1638765 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  H0508_RS08430 (STHERMO_1892) - 1639014..1640207 (-) 1194 WP_022096898.1 acetate kinase -
  H0508_RS08435 (STHERMO_1893) comYH 1640263..1641219 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H0508_RS08440 (STHERMO_1894) comGG 1641264..1641581 (-) 318 WP_011226623.1 competence type IV pilus minor pilin ComGG -
  H0508_RS08445 (STHERMO_1895) comYF 1641559..1641996 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0508_RS08450 (STHERMO_1896) comGE 1641980..1642273 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  H0508_RS08455 (STHERMO_1897) comYD 1642245..1642673 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H0508_RS08460 (STHERMO_1898) comYC 1642633..1642959 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H0508_RS08465 (STHERMO_1899) comYB 1642956..1644056 (-) 1101 WP_148148900.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0508_RS08470 (STHERMO_1900) comGA/cglA/cilD 1643938..1644879 (-) 942 WP_011226629.1 competence type IV pilus ATPase ComGA Machinery gene
  H0508_RS08475 (STHERMO_1901) - 1644960..1645322 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41754.88 Da        Isoelectric Point: 10.0449

>NTDB_id=1130877 H0508_RS08465 WP_148148900.1 1642956..1644056(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_36]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1130877 H0508_RS08465 WP_148148900.1 1642956..1644056(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_36]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.678

93.443

0.511
  comYB Streptococcus mutans UA159

54.678

93.443

0.511
  comYB Streptococcus gordonii str. Challis substr. CH1

51.17

93.443

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.453

90.437

0.456
  comGB/cglB Streptococcus mitis SK321

49.697

90.164

0.448
  comGB/cglB Streptococcus pneumoniae Rx1

49.394

90.164

0.445
  comGB/cglB Streptococcus pneumoniae D39

49.394

90.164

0.445
  comGB/cglB Streptococcus pneumoniae R6

49.394

90.164

0.445
  comGB/cglB Streptococcus pneumoniae TIGR4

49.394

90.164

0.445
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413

Multiple sequence alignment