Detailed information NTG1130874

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H0508_RS08445
• Genome accession: NZ_LR822014
• Coordinates: 1641559..1641996 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_36
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1636559..1646996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0508_RS08410 (STHERMO_1886)	-	1636613..1637275 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
H0508_RS08415 (STHERMO_1888)	-	1637378..1637826 (-)	449	Protein_1617	CAAX protease	-
H0508_RS09760 (STHERMO_1889)	-	1637900..1638325 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
H0508_RS08425 (STHERMO_1891)	-	1638568..1638765 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
H0508_RS08430 (STHERMO_1892)	-	1639014..1640207 (-)	1194	WP_022096898.1	acetate kinase	-
H0508_RS08435 (STHERMO_1893)	comYH	1640263..1641219 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H0508_RS08440 (STHERMO_1894)	comGG	1641264..1641581 (-)	318	WP_011226623.1	competence type IV pilus minor pilin ComGG	-
H0508_RS08445 (STHERMO_1895)	comYF	1641559..1641996 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0508_RS08450 (STHERMO_1896)	comGE	1641980..1642273 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H0508_RS08455 (STHERMO_1897)	comYD	1642245..1642673 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H0508_RS08460 (STHERMO_1898)	comYC	1642633..1642959 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H0508_RS08465 (STHERMO_1899)	comYB	1642956..1644056 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0508_RS08470 (STHERMO_1900)	comGA/cglA/cilD	1643938..1644879 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
H0508_RS08475 (STHERMO_1901)	-	1644960..1645322 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=1130874 H0508_RS08445 WP_014608742.1 1641559..1641996(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_36]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1130874 H0508_RS08445 WP_014608742.1 1641559..1641996(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_36]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441