Detailed information NTG1130804

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: H0502_RS07320
• Genome accession: NZ_LR822013
• Coordinates: 1458328..1459077 (-)
• Length: 249 a.a.
• NCBI ID: WP_179970775.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_32
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1453328..1464077

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0502_RS07300 (STHERMO_1686)	-	1453652..1454884 (-)	1233	WP_011225367.1	cysteine desulfurase	-
H0502_RS07305 (STHERMO_1687)	sufD	1454938..1456200 (-)	1263	WP_002947640.1	Fe-S cluster assembly protein SufD	-
H0502_RS07310 (STHERMO_1688)	sufC	1456237..1457007 (-)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
H0502_RS07315 (STHERMO_1689)	-	1457167..1458324 (-)	1158	WP_167401408.1	glycosyltransferase family 4 protein	-
H0502_RS07320 (STHERMO_1690)	mecA	1458328..1459077 (-)	750	WP_179970775.1	adaptor protein MecA	Regulator
H0502_RS07325	-	1459361..1459558 (+)	198	WP_224103664.1	DUF3021 family protein	-
H0502_RS07330 (STHERMO_1691)	-	1459704..1460558 (-)	855	WP_041828107.1	undecaprenyl-diphosphate phosphatase	-
H0502_RS07335 (STHERMO_1692)	-	1460761..1462311 (+)	1551	WP_014607891.1	ABC transporter substrate-binding protein/permease	-
H0502_RS07340 (STHERMO_1693)	-	1462311..1463051 (+)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
H0502_RS10470 (STHERMO_1694)	-	1463138..1463245 (-)	108	WP_011226802.1	LPXTG cell wall anchor domain-containing protein	-
H0502_RS07350 (STHERMO_1695)	-	1463332..1463502 (-)	171	WP_011680664.1	hypothetical protein	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29147.66 Da
• Isoelectric Point: 4.0659

>NTDB_id=1130804 H0502_RS07320 WP_179970775.1 1458328..1459077(-) (mecA) [Streptococcus thermophilus isolate STH_CIRM_32]
MEMKQINETTLKIMITMEDLEEHGMELKDFLISQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=1130804 H0502_RS07320 WP_179970775.1 1458328..1459077(-) (mecA) [Streptococcus thermophilus isolate STH_CIRM_32]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTTCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMG 18311	99.598	100	0.996
mecA	Streptococcus thermophilus LMD-9	98.795	100	0.988
mecA	Streptococcus mutans UA159	56.967	97.992	0.558
mecA	Streptococcus pneumoniae Rx1	45.783	100	0.458
mecA	Streptococcus pneumoniae D39	45.783	100	0.458
mecA	Streptococcus pneumoniae R6	45.783	100	0.458
mecA	Streptococcus pneumoniae TIGR4	45.783	100	0.458