Detailed information NTG1130760

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H0505_RS09340
• Genome accession: NZ_LR822012
• Coordinates: 1799106..1800341 (+)
• Length: 411 a.a.
• NCBI ID: WP_179971114.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_30
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1794106..1805341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0505_RS09310 (STHERMO_2060)	-	1794572..1797178 (+)	2607	WP_179971113.1	YfhO family protein	-
H0505_RS09330 (STHERMO_2061)	-	1797723..1798406 (-)	684	WP_164178359.1	YoaK family protein	-
H0505_RS09335 (STHERMO_2062)	rlmH	1798422..1798901 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H0505_RS09340 (STHERMO_2063)	htrA	1799106..1800341 (+)	1236	WP_179971114.1	S1C family serine protease	Regulator
H0505_RS09345 (STHERMO_2064)	spo0J	1800407..1801174 (+)	768	WP_179971115.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42854.15 Da
• Isoelectric Point: 4.7654

>NTDB_id=1130760 H0505_RS09340 WP_179971114.1 1799106..1800341(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_30]
MKKFNWKKIVAPIAILIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGNSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKLSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1130760 H0505_RS09340 WP_179971114.1 1799106..1800341(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATACTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGAACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCATGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAATTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (4-406)

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.854	100	0.599
htrA	Streptococcus gordonii str. Challis substr. CH1	56.796	100	0.569
htrA	Streptococcus mitis NCTC 12261	53.301	99.513	0.53
htrA	Streptococcus pneumoniae TIGR4	53.056	99.513	0.528
htrA	Streptococcus pneumoniae D39	53.056	99.513	0.528
htrA	Streptococcus pneumoniae Rx1	53.056	99.513	0.528
htrA	Streptococcus pneumoniae R6	53.056	99.513	0.528