Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H0505_RS01615 Genome accession   NZ_LR822012
Coordinates   295941..296630 (+) Length   229 a.a.
NCBI ID   WP_179971180.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_30     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 290941..301630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0505_RS09490 - 291907..292077 (+) 171 Protein_264 ascorbate 6-phosphate lactonase -
  H0505_RS01595 (STHERMO_0323) - 292094..292765 (-) 672 WP_002946492.1 potassium channel family protein -
  H0505_RS01600 (STHERMO_0324) - 292805..294169 (-) 1365 WP_269472517.1 TrkH family potassium uptake protein -
  H0505_RS01605 (STHERMO_0325) rsmG 294239..294952 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H0505_RS01610 (STHERMO_0326) - 295249..295785 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  H0505_RS01615 (STHERMO_0327) covR 295941..296630 (+) 690 WP_179971180.1 response regulator transcription factor Regulator
  H0505_RS01620 (STHERMO_0328) covS 296627..298144 (+) 1518 WP_179971181.1 HAMP domain-containing histidine kinase Regulator
  H0505_RS01625 (STHERMO_0329) nrdR 298266..298745 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  H0505_RS01630 (STHERMO_0330) - 298742..299917 (+) 1176 WP_002949643.1 DnaD domain protein -
  H0505_RS01635 (STHERMO_0331) dnaI 299921..300823 (+) 903 WP_002946786.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26671.77 Da        Isoelectric Point: 4.7059

>NTDB_id=1130717 H0505_RS01615 WP_179971180.1 295941..296630(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_30]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKSSTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1130717 H0505_RS01615 WP_179971180.1 295941..296630(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGATGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAATCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment