Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   H0505_RS01620 Genome accession   NZ_LR822012
Coordinates   296627..298144 (+) Length   505 a.a.
NCBI ID   WP_179971181.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_30     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 291627..303144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0505_RS09490 - 291907..292077 (+) 171 Protein_264 ascorbate 6-phosphate lactonase -
  H0505_RS01595 (STHERMO_0323) - 292094..292765 (-) 672 WP_002946492.1 potassium channel family protein -
  H0505_RS01600 (STHERMO_0324) - 292805..294169 (-) 1365 WP_269472517.1 TrkH family potassium uptake protein -
  H0505_RS01605 (STHERMO_0325) rsmG 294239..294952 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H0505_RS01610 (STHERMO_0326) - 295249..295785 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  H0505_RS01615 (STHERMO_0327) covR 295941..296630 (+) 690 WP_179971180.1 response regulator transcription factor Regulator
  H0505_RS01620 (STHERMO_0328) covS 296627..298144 (+) 1518 WP_179971181.1 HAMP domain-containing histidine kinase Regulator
  H0505_RS01625 (STHERMO_0329) nrdR 298266..298745 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  H0505_RS01630 (STHERMO_0330) - 298742..299917 (+) 1176 WP_002949643.1 DnaD domain protein -
  H0505_RS01635 (STHERMO_0331) dnaI 299921..300823 (+) 903 WP_002946786.1 primosomal protein DnaI -
  H0505_RS01640 (STHERMO_0332) der 300929..302239 (+) 1311 WP_011680741.1 ribosome biogenesis GTPase Der -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57570.00 Da        Isoelectric Point: 5.2750

>NTDB_id=1130718 H0505_RS01620 WP_179971181.1 296627..298144(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_30]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTIVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESRDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1130718 H0505_RS01620 WP_179971181.1 296627..298144(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTATAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCGTGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(213-265)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.223

99.406

0.937

Multiple sequence alignment