Detailed information
Bioinformatically predicted
Overview
| Name | amiA3 | Type | Regulator |
| Locus tag | H0504_RS02430 | Genome accession | NZ_LR822011 |
| Coordinates | 461966..463939 (+) | Length | 657 a.a. |
| NCBI ID | WP_011226306.1 | Uniprot ID | Q5M3H2 |
| Organism | Streptococcus thermophilus isolate STH_CIRM_23 | ||
| Function | binding to XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 417501..487589 | 461966..463939 | within | 0 |
| IScluster/Tn | 457870..465233 | 461966..463939 | within | 0 |
Gene organization within MGE regions
Location: 417501..487589
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H0504_RS02210 (STHERMO_0470) | - | 417599..418339 (-) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
| H0504_RS02215 (STHERMO_0471) | - | 418339..420549 (-) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| H0504_RS09995 | - | 420748..421684 (+) | 937 | Protein_403 | CPBP family intramembrane glutamic endopeptidase | - |
| H0504_RS02230 (STHERMO_0476) | uvrB | 422371..424362 (+) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| H0504_RS02235 (STHERMO_0477) | - | 424407..424871 (+) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| H0504_RS02240 (STHERMO_0478) | - | 425084..425914 (+) | 831 | WP_041828297.1 | transporter substrate-binding domain-containing protein | - |
| H0504_RS02245 (STHERMO_0479) | - | 425911..426708 (+) | 798 | WP_011226343.1 | transporter substrate-binding domain-containing protein | - |
| H0504_RS02250 (STHERMO_0480) | - | 427055..428164 (+) | 1110 | WP_041828295.1 | aminotransferase | - |
| H0504_RS02255 (STHERMO_0481) | - | 428257..429051 (+) | 795 | WP_011226341.1 | transporter substrate-binding domain-containing protein | - |
| H0504_RS02260 (STHERMO_0482) | rpsU | 429246..429422 (+) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| H0504_RS02265 (STHERMO_0483) | dnaG | 429793..431604 (+) | 1812 | WP_011226339.1 | DNA primase | - |
| H0504_RS02270 (STHERMO_0484) | rpoD | 431608..432717 (+) | 1110 | WP_011226338.1 | RNA polymerase sigma factor RpoD | - |
| H0504_RS02275 (STHERMO_0485) | - | 432771..433106 (+) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| H0504_RS02280 (STHERMO_0487) | - | 433440..434855 (+) | 1416 | WP_096811580.1 | DUF2142 domain-containing protein | - |
| H0504_RS02285 (STHERMO_0488) | - | 434918..435835 (+) | 918 | WP_375708565.1 | glycosyltransferase family 2 protein | - |
| H0504_RS02290 (STHERMO_0490) | - | 435948..437282 (+) | 1335 | WP_179971768.1 | DUF6056 family protein | - |
| H0504_RS02295 (STHERMO_0491) | rfbD | 437359..438210 (+) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| H0504_RS02300 (STHERMO_0492) | - | 438287..438982 (+) | 696 | WP_171073564.1 | glycosyltransferase family 2 protein | - |
| H0504_RS02305 (STHERMO_0493) | - | 438988..439320 (+) | 333 | WP_011226332.1 | DUF2304 domain-containing protein | - |
| H0504_RS02310 (STHERMO_0494) | - | 439313..440587 (+) | 1275 | WP_179971769.1 | lipopolysaccharide biosynthesis protein | - |
| H0504_RS02315 (STHERMO_0495) | - | 440587..441597 (+) | 1011 | WP_011226330.1 | glycosyltransferase family 2 protein | - |
| H0504_RS02320 (STHERMO_0496) | cps2T | 441706..442854 (+) | 1149 | WP_002948014.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| H0504_RS02325 (STHERMO_0497) | - | 442851..443807 (+) | 957 | WP_011226328.1 | glycosyltransferase family 2 protein | - |
| H0504_RS02330 (STHERMO_0498) | - | 443791..444600 (+) | 810 | WP_002948020.1 | ABC transporter permease | - |
| H0504_RS02335 (STHERMO_0499) | - | 444600..445805 (+) | 1206 | WP_179971770.1 | ABC transporter ATP-binding protein | - |
| H0504_RS02340 (STHERMO_0500) | - | 445825..446880 (+) | 1056 | WP_179971771.1 | glycosyltransferase family 2 protein | - |
| H0504_RS02345 (STHERMO_0501) | - | 446877..448661 (+) | 1785 | WP_179971772.1 | rhamnan synthesis F family protein | - |
| H0504_RS02350 (STHERMO_0502) | radC | 448710..449396 (+) | 687 | WP_179971773.1 | RadC family protein | - |
| H0504_RS02355 (STHERMO_0503) | - | 449449..450144 (-) | 696 | WP_096811574.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| H0504_RS02360 (STHERMO_0504) | - | 450137..450796 (-) | 660 | WP_179971774.1 | redox-sensing transcriptional repressor Rex | - |
| H0504_RS02365 (STHERMO_0505) | - | 450940..451287 (-) | 348 | WP_014608555.1 | DUF1831 domain-containing protein | - |
| H0504_RS02370 (STHERMO_0506) | - | 451289..452401 (-) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| H0504_RS02375 (STHERMO_0507) | - | 452405..453376 (-) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| H0504_RS02380 (STHERMO_0508) | - | 453741..454316 (-) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| H0504_RS02385 (STHERMO_0509) | - | 454412..455086 (+) | 675 | WP_002951443.1 | GTP pyrophosphokinase family protein | - |
| H0504_RS02390 (STHERMO_0510) | - | 455058..455894 (+) | 837 | WP_041827075.1 | NAD kinase | - |
| H0504_RS02395 (STHERMO_0511) | - | 455891..456787 (+) | 897 | WP_011226316.1 | RluA family pseudouridine synthase | - |
| H0504_RS02400 (STHERMO_0512) | pta | 456801..457784 (+) | 984 | WP_011226315.1 | phosphate acetyltransferase | - |
| H0504_RS02405 | - | 457870..459221 (+) | 1352 | Protein_439 | IS3 family transposase | - |
| H0504_RS02410 (STHERMO_0517) | - | 459267..460472 (-) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| H0504_RS02415 | - | 460822..461136 (+) | 315 | Protein_441 | TatD family hydrolase | - |
| H0504_RS02420 (STHERMO_0519) | - | 461168..461578 (+) | 411 | Protein_442 | ATP-binding cassette domain-containing protein | - |
| H0504_RS02425 | - | 461572..461762 (+) | 191 | Protein_443 | IS3 family transposase | - |
| H0504_RS02430 (STHERMO_0520) | amiA3 | 461966..463939 (+) | 1974 | WP_011226306.1 | peptide ABC transporter substrate-binding protein | Regulator |
| H0504_RS02435 (STHERMO_0521) | - | 463984..465233 (-) | 1250 | Protein_445 | ISL3 family transposase | - |
| H0504_RS02445 (STHERMO_0522) | amiA | 465589..467556 (+) | 1968 | WP_179971753.1 | peptide ABC transporter substrate-binding protein | Regulator |
| H0504_RS02450 (STHERMO_0523) | amiC | 467618..469111 (+) | 1494 | WP_011227407.1 | ABC transporter permease | Regulator |
| H0504_RS02455 (STHERMO_0524) | amiD | 469111..470037 (+) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| H0504_RS02460 (STHERMO_0525) | amiE | 470047..471132 (+) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| H0504_RS02465 (STHERMO_0526) | amiF | 471125..472054 (+) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| H0504_RS02470 (STHERMO_0527) | - | 472104..472889 (-) | 786 | WP_002951425.1 | hypothetical protein | - |
| H0504_RS02475 (STHERMO_0528) | - | 472901..473599 (-) | 699 | WP_179971775.1 | ABC transporter ATP-binding protein | - |
| H0504_RS02480 (STHERMO_0529) | - | 473604..473981 (-) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| H0504_RS02485 (STHERMO_0531) | - | 474165..474959 (+) | 795 | WP_011226299.1 | HAD hydrolase family protein | - |
| H0504_RS02490 (STHERMO_0532) | - | 474952..475767 (+) | 816 | WP_011226298.1 | Cof-type HAD-IIB family hydrolase | - |
| H0504_RS02495 (STHERMO_0533) | ftsY | 475781..477172 (+) | 1392 | WP_011226297.1 | signal recognition particle-docking protein FtsY | - |
| H0504_RS02500 (STHERMO_0534) | gmk | 477405..478034 (+) | 630 | WP_011226296.1 | guanylate kinase | - |
| H0504_RS02505 (STHERMO_0535) | rpoZ | 478056..478370 (+) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| H0504_RS02510 (STHERMO_0536) | - | 478512..480908 (+) | 2397 | WP_011226295.1 | primosomal protein N' | - |
| H0504_RS02515 (STHERMO_0537) | fmt | 480926..481861 (+) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| H0504_RS02520 (STHERMO_0538) | rsmB | 481851..483173 (+) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| H0504_RS02525 (STHERMO_0539) | - | 483217..483954 (+) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| H0504_RS02530 (STHERMO_0540) | stkP/pknB | 483954..485825 (+) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| H0504_RS09495 (STHERMO_0543) | - | 486462..486617 (+) | 156 | WP_011226290.1 | ion channel | - |
| H0504_RS02540 (STHERMO_0544) | liaF | 486883..487581 (+) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
Sequence
Protein
Download Length: 657 a.a. Molecular weight: 72286.26 Da Isoelectric Point: 5.1005
>NTDB_id=1130656 H0504_RS02430 WP_011226306.1 461966..463939(+) (amiA3) [Streptococcus thermophilus isolate STH_CIRM_23]
MKKSKWLALAGVALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDEYTLQYTLKQPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIYYTAPGASTSAIGINLDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLAVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNF
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVDQSSKLNVAQAQSLKQTIEKSLGSENVVIDINQLSSDDLEN
VTLNAANAAAEDWDISNSVAWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPAISRLTPFTGASLQVGDKNSSNDYIKYVKPQEKVVTKKEYEQSREKWLKE
KKESNEKAQKDLEKHVK
MKKSKWLALAGVALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDEYTLQYTLKQPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIYYTAPGASTSAIGINLDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLAVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNF
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVDQSSKLNVAQAQSLKQTIEKSLGSENVVIDINQLSSDDLEN
VTLNAANAAAEDWDISNSVAWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPAISRLTPFTGASLQVGDKNSSNDYIKYVKPQEKVVTKKEYEQSREKWLKE
KKESNEKAQKDLEKHVK
Nucleotide
Download Length: 1974 bp
>NTDB_id=1130656 H0504_RS02430 WP_011226306.1 461966..463939(+) (amiA3) [Streptococcus thermophilus isolate STH_CIRM_23]
ATGAAAAAAAGCAAATGGTTGGCTCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTATGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGAGTATACTTTGCAGTACACGCTTAAGCAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAAGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATTAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACGAGTTCAAACTATGCTTCTGTAGAGAAGAAATATAAAGATAATATTTATT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATCTTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGCTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATTTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTGACCAAAGCTCTAAACTTAATGTTGCCCAAGCCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GTAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGCTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCCTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGCTATCTCACGCTTGACACCGTTTACCGGTGCTAGCCTCCAGGTGGGTGATAAAAACTCATCAAACGACT
ACATCAAATATGTGAAACCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAA
AAGAAAGAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
ATGAAAAAAAGCAAATGGTTGGCTCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTATGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGAGTATACTTTGCAGTACACGCTTAAGCAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAAGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATTAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACGAGTTCAAACTATGCTTCTGTAGAGAAGAAATATAAAGATAATATTTATT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATCTTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGCTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATTTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTGACCAAAGCTCTAAACTTAATGTTGCCCAAGCCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GTAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGCTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCCTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGCTATCTCACGCTTGACACCGTTTACCGGTGCTAGCCTCCAGGTGGGTGATAAAAACTCATCAAACGACT
ACATCAAATATGTGAAACCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAA
AAGAAAGAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiA3 | Streptococcus thermophilus LMG 18311 |
100 |
100 |
1 |
| amiA3 | Streptococcus thermophilus LMD-9 |
98.478 |
100 |
0.985 |
| amiA | Streptococcus salivarius strain HSISS4 |
90.563 |
100 |
0.906 |