Detailed information NTG1130641

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: H0507_RS08700
• Genome accession: NZ_LR822010
• Coordinates: 1666427..1667527 (-)
• Length: 366 a.a.
• NCBI ID: WP_148148900.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_29
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1661427..1672527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0507_RS08660 (STHERMO_1927)	-	1662039..1662236 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
H0507_RS08665 (STHERMO_1928)	-	1662485..1663678 (-)	1194	WP_022096898.1	acetate kinase	-
H0507_RS08670 (STHERMO_1929)	comYH	1663734..1664690 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H0507_RS08675 (STHERMO_1930)	comGG	1664735..1665052 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
H0507_RS08680 (STHERMO_1931)	comYF	1665030..1665467 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0507_RS08685 (STHERMO_1932)	comGE	1665451..1665744 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H0507_RS08690 (STHERMO_1933)	comYD	1665716..1666144 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H0507_RS08695 (STHERMO_1934)	comYC	1666104..1666430 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H0507_RS08700 (STHERMO_1935)	comYB	1666427..1667527 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0507_RS08705 (STHERMO_1936)	comGA/cglA/cilD	1667409..1668350 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
H0507_RS08710 (STHERMO_1937)	-	1668431..1668793 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41754.88 Da
• Isoelectric Point: 10.0449

>NTDB_id=1130641 H0507_RS08700 WP_148148900.1 1666427..1667527(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_29]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=1130641 H0507_RS08700 WP_148148900.1 1666427..1667527(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_29]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.394	90.164	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413