Detailed information NTG1130638

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H0507_RS08680
• Genome accession: NZ_LR822010
• Coordinates: 1665030..1665467 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_29
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1660030..1670467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0507_RS08645 (STHERMO_1922)	-	1660084..1660746 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
H0507_RS08650 (STHERMO_1924)	-	1660849..1661297 (-)	449	Protein_1641	CAAX protease	-
H0507_RS10005 (STHERMO_1925)	-	1661371..1661796 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
H0507_RS08660 (STHERMO_1927)	-	1662039..1662236 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
H0507_RS08665 (STHERMO_1928)	-	1662485..1663678 (-)	1194	WP_022096898.1	acetate kinase	-
H0507_RS08670 (STHERMO_1929)	comYH	1663734..1664690 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
H0507_RS08675 (STHERMO_1930)	comGG	1664735..1665052 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
H0507_RS08680 (STHERMO_1931)	comYF	1665030..1665467 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0507_RS08685 (STHERMO_1932)	comGE	1665451..1665744 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H0507_RS08690 (STHERMO_1933)	comYD	1665716..1666144 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H0507_RS08695 (STHERMO_1934)	comYC	1666104..1666430 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H0507_RS08700 (STHERMO_1935)	comYB	1666427..1667527 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0507_RS08705 (STHERMO_1936)	comGA/cglA/cilD	1667409..1668350 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
H0507_RS08710 (STHERMO_1937)	-	1668431..1668793 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=1130638 H0507_RS08680 WP_014608742.1 1665030..1665467(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_29]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1130638 H0507_RS08680 WP_014608742.1 1665030..1665467(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_29]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441