Detailed information NTG1130535

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: H0503_RS00945
• Genome accession: NZ_LR822009
• Coordinates: 170521..171270 (+)
• Length: 249 a.a.
• NCBI ID: WP_179970775.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_19
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 165521..176270

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0503_RS00915 (STHERMO_0176)	-	166096..166266 (+)	171	WP_011680664.1	hypothetical protein	-
H0503_RS00920	-	166353..166460 (+)	108	WP_011226802.1	LPXTG cell wall anchor domain-containing protein	-
H0503_RS00925 (STHERMO_0177)	-	166547..167287 (-)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
H0503_RS00930 (STHERMO_0178)	-	167287..168837 (-)	1551	WP_014607891.1	ABC transporter substrate-binding protein/permease	-
H0503_RS00935 (STHERMO_0179)	-	169040..169894 (+)	855	WP_041828107.1	undecaprenyl-diphosphate phosphatase	-
H0503_RS00940	-	170040..170255 (-)	216	WP_011226805.1	DUF3021 family protein	-
H0503_RS00945 (STHERMO_0180)	mecA	170521..171270 (+)	750	WP_179970775.1	adaptor protein MecA	Regulator
H0503_RS00950 (STHERMO_0181)	-	171274..172431 (+)	1158	WP_167401408.1	glycosyltransferase family 4 protein	-
H0503_RS00955 (STHERMO_0182)	sufC	172591..173361 (+)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
H0503_RS00960 (STHERMO_0183)	sufD	173398..174660 (+)	1263	WP_002947640.1	Fe-S cluster assembly protein SufD	-
H0503_RS00965 (STHERMO_0184)	-	174714..175946 (+)	1233	WP_011225367.1	cysteine desulfurase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29147.66 Da
• Isoelectric Point: 4.0659

>NTDB_id=1130535 H0503_RS00945 WP_179970775.1 170521..171270(+) (mecA) [Streptococcus thermophilus isolate STH_CIRM_19]
MEMKQINETTLKIMITMEDLEEHGMELKDFLISQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=1130535 H0503_RS00945 WP_179970775.1 170521..171270(+) (mecA) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTTCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMG 18311	99.598	100	0.996
mecA	Streptococcus thermophilus LMD-9	98.795	100	0.988
mecA	Streptococcus mutans UA159	56.967	97.992	0.558
mecA	Streptococcus pneumoniae Rx1	45.783	100	0.458
mecA	Streptococcus pneumoniae D39	45.783	100	0.458
mecA	Streptococcus pneumoniae R6	45.783	100	0.458
mecA	Streptococcus pneumoniae TIGR4	45.783	100	0.458