Detailed information NTG1130526

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H0501_RS09665
• Genome accession: NZ_LR822008
• Coordinates: 1857763..1858998 (+)
• Length: 411 a.a.
• NCBI ID: WP_014608809.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_18
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1852763..1863998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0501_RS09635 (STHERMO_2147)	-	1853231..1855837 (+)	2607	WP_041827400.1	YfhO family protein	-
H0501_RS09655 (STHERMO_2148)	-	1856380..1857063 (-)	684	WP_011226711.1	YoaK family protein	-
H0501_RS09660 (STHERMO_2149)	rlmH	1857079..1857558 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H0501_RS09665 (STHERMO_2150)	htrA	1857763..1858998 (+)	1236	WP_014608809.1	S1C family serine protease	Regulator
H0501_RS09670 (STHERMO_2151)	spo0J	1859064..1859831 (+)	768	WP_002952299.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.25 Da
• Isoelectric Point: 4.7061

>NTDB_id=1130526 H0501_RS09665 WP_014608809.1 1857763..1858998(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_18]
MKKFNWKKIVVPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTVKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1130526 H0501_RS09665 WP_014608809.1 1857763..1858998(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_18]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGTGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGTTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTCGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATTGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (6-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.097	100	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus mitis NCTC 12261	53.79	99.513	0.535
htrA	Streptococcus pneumoniae TIGR4	53.545	99.513	0.533
htrA	Streptococcus pneumoniae D39	53.545	99.513	0.533
htrA	Streptococcus pneumoniae Rx1	53.545	99.513	0.533
htrA	Streptococcus pneumoniae R6	53.545	99.513	0.533