Detailed information NTG1130463

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STHERMO_RS08650
• Genome accession: NZ_LR822006
• Coordinates: 1664421..1664858 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_16
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1659421..1669858

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STHERMO_RS08615 (STHERMO_1929)	-	1659475..1660137 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
STHERMO_RS08620 (STHERMO_1931)	-	1660240..1660688 (-)	449	Protein_1642	CAAX protease	-
STHERMO_RS09945 (STHERMO_1932)	-	1660762..1661187 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
STHERMO_RS08630 (STHERMO_1934)	-	1661430..1661627 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STHERMO_RS08635 (STHERMO_1935)	-	1661876..1663069 (-)	1194	WP_022096898.1	acetate kinase	-
STHERMO_RS08640 (STHERMO_1936)	comYH	1663125..1664081 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STHERMO_RS08645 (STHERMO_1937)	comGG	1664126..1664443 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STHERMO_RS08650 (STHERMO_1938)	comYF	1664421..1664858 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
STHERMO_RS08655 (STHERMO_1939)	comGE	1664842..1665135 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STHERMO_RS08660 (STHERMO_1940)	comYD	1665107..1665535 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STHERMO_RS08665 (STHERMO_1941)	comYC	1665495..1665821 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STHERMO_RS08670 (STHERMO_1942)	comYB	1665818..1666918 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
STHERMO_RS08675 (STHERMO_1943)	comGA/cglA/cilD	1666800..1667741 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
STHERMO_RS08680 (STHERMO_1944)	-	1667822..1668184 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=1130463 STHERMO_RS08650 WP_014608742.1 1664421..1664858(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_16]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1130463 STHERMO_RS08650 WP_014608742.1 1664421..1664858(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_16]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441