Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GPW69_RS08935 Genome accession   NZ_LR738724
Coordinates   1831081..1831803 (-) Length   240 a.a.
NCBI ID   WP_074391665.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1826081..1836803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS08915 - 1826237..1827460 (-) 1224 WP_044673924.1 cysteine desulfurase -
  GPW69_RS08920 sufD 1827464..1828726 (-) 1263 WP_074391935.1 Fe-S cluster assembly protein SufD -
  GPW69_RS08925 sufC 1828743..1829516 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  GPW69_RS08930 - 1829912..1831084 (-) 1173 WP_024414291.1 glycosyltransferase family 4 protein -
  GPW69_RS08935 mecA 1831081..1831803 (-) 723 WP_074391665.1 adaptor protein MecA Regulator
  GPW69_RS08940 - 1831931..1832767 (-) 837 WP_014638628.1 undecaprenyl-diphosphate phosphatase -
  GPW69_RS08945 - 1832894..1834459 (+) 1566 WP_044673918.1 ABC transporter substrate-binding protein/permease -
  GPW69_RS08950 - 1834452..1835195 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  GPW69_RS08955 - 1835320..1835529 (-) 210 WP_009910800.1 hypothetical protein -
  GPW69_RS08960 - 1835612..1836517 (-) 906 WP_074391664.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27948.52 Da        Isoelectric Point: 4.0169

>NTDB_id=1129616 GPW69_RS08935 WP_074391665.1 1831081..1831803(-) (mecA) [Streptococcus suis isolate 9401240]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEVDEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENCSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=1129616 GPW69_RS08935 WP_074391665.1 1831081..1831803(-) (mecA) [Streptococcus suis isolate 9401240]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTAACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGTAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTATTTGACCGTTCTTAT
CAATGTAGAAAATTGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGGATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

48.333

100

0.483
  mecA Streptococcus thermophilus LMG 18311

47.917

100

0.479

Multiple sequence alignment