Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   GPW69_RS03420 Genome accession   NZ_LR738724
Coordinates   666178..668415 (+) Length   745 a.a.
NCBI ID   WP_074391485.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 661178..673415
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS03400 - 661924..662709 (-) 786 WP_074391489.1 ABC transporter ATP-binding protein -
  GPW69_RS03405 - 662861..664306 (-) 1446 WP_074391488.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  GPW69_RS03410 - 664718..665464 (+) 747 WP_074391487.1 lysophospholipid acyltransferase family protein -
  GPW69_RS03415 - 665532..666194 (+) 663 WP_074391486.1 helix-hairpin-helix domain-containing protein -
  GPW69_RS03420 comEC/celB 666178..668415 (+) 2238 WP_074391485.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83853.49 Da        Isoelectric Point: 6.6706

>NTDB_id=1129593 GPW69_RS03420 WP_074391485.1 666178..668415(+) (comEC/celB) [Streptococcus suis isolate 9401240]
MSRSIKLPCQPIHLAVLAVAAYFTVHSFSLLTMGLLSLLLVVFGFRQGKAVFLRTLPLLALCGLFFGCQKVQWERAAQSA
PEQVSTVQAIPDTIDINGDSLSFRGRADGQTYQVFYKLASQEEQAYFQKLTGLVQLEVEAEVSLPAGQRNFNGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNIFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLSLTKEIVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLML
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAVVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPLVKMTWVNGFFVFMEKIIVWVADLGFRSWILGKPSGLVLLLLLVSLFLLYDFHRKKKWLLGLSLVLALLFFTTK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEEWQERSSQANAERTLIPYLHSQGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGQIYVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLIESYPQLPVDVLKAGHHGSQGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=1129593 GPW69_RS03420 WP_074391485.1 666178..668415(+) (comEC/celB) [Streptococcus suis isolate 9401240]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTCTTGGCGGTGGCGGCCTACTTTACAGTCCACTC
ATTTTCCCTCTTGACAATGGGCCTACTGAGTCTGTTACTAGTTGTCTTTGGGTTTCGGCAAGGTAAGGCGGTGTTCCTCA
GAACGCTGCCGCTTCTAGCCCTGTGCGGTCTCTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGCCCAGTCAGCC
CCAGAGCAAGTGTCGACTGTGCAGGCTATTCCCGATACCATAGACATCAATGGCGACAGCCTGTCTTTTCGGGGTCGGGC
TGATGGACAAACCTATCAGGTTTTCTACAAGTTAGCCAGTCAAGAGGAGCAGGCCTATTTTCAAAAGCTGACAGGTCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGTCTGCCAGCAGGTCAGCGGAATTTTAATGGCTTTGACTATCAAGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACAGCGATTAAGAAGATTGTTCCTGTCCAGTCTTGGAACATTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGAGCTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTTTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTTTGAGCTTGACCAAGGAAAT
CGTAGATAAGTTGCAGATTCCCTTTTCTCTTGTCTATGCTGGTTTGACAGGCTTTTCGGTGTCAGTGGTGCGGTCGCTGG
TCCAAAAAATTCTGGGGAATATGGGCTTGCGGAAGCTGGATAATTTTGCGGTGACGGTCTTTGTCTGTCTGCTGATGCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGTGGTGGAAAGTCTCAGTATCTCGCTGGGGATTCTACCTGTGCTCATGACCTATTTCTATG
CCTTCCAGCCTCTGTCCATTCTCCTGACCTTTGCCTTTTCTTTTGTCTTTGATGTTCTGCTCTTGCCAGGTTTGTCAGTT
ATTTTTCTCCTGTCACCTCTGGTCAAGATGACTTGGGTCAACGGATTTTTTGTTTTTATGGAAAAAATCATTGTCTGGGT
GGCAGATTTGGGATTTCGGTCTTGGATACTGGGCAAACCGTCTGGGCTGGTTCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAAGAAAAAATGGCTTCTAGGACTAAGCCTGGTCCTCGCTCTGCTATTTTTCACGACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGTGGTCGGGTCGATTTTGCGGCCAAGGAGGAGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACCTTGATTCCCTATCTGCATAGTCAGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCATACCGATACGGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTCCAAATTGGTCAAATTTACGTGTCGCCTGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACATTGAAAGAAATCAATGTCCCTGTTCATGTAGTGAAAGTGGGCGACCGCTTGCCGATTTTTGACT
CTTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCTGTTGTCCTTTACGGTCGCTTGTTG
GAAACTAATTTTCTCTTTACAGGGGATTTGGAGCAGGGGGAGCTGGATTTGATAGAAAGCTATCCGCAGCTACCTGTTGA
TGTCCTCAAAGCTGGTCACCACGGCTCCCAAGGCTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCC
TGGTATCAGCAGGAGAAAACAACCGCTACAAGCACCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGAAATATCCAA
GTCTATCGCACCGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAAGAGTGGAGGATTGAAACGGTGAGGGAGTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Domain of unknown function (DUF4131) (DUF4131)

(28-175)

Competence protein (Competence)

(215-460)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.432

99.732

0.533
  comEC/celB Streptococcus mitis NCTC 12261

52.497

99.463

0.522
  comEC/celB Streptococcus pneumoniae TIGR4

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae Rx1

51.348

99.597

0.511
  comEC/celB Streptococcus pneumoniae D39

51.348

99.597

0.511
  comEC/celB Streptococcus pneumoniae R6

51.348

99.597

0.511
  comEC Lactococcus lactis subsp. cremoris KW2

48.461

100

0.486

Multiple sequence alignment