Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   GPW69_RS00365 Genome accession   NZ_LR738724
Coordinates   58431..59330 (+) Length   299 a.a.
NCBI ID   WP_074391038.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53431..64330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS00335 - 53761..54507 (-) 747 WP_074391034.1 amino acid ABC transporter ATP-binding protein -
  GPW69_RS00340 - 54512..55189 (-) 678 WP_074391035.1 amino acid ABC transporter permease -
  GPW69_RS00345 - 55170..55829 (-) 660 WP_074391045.1 amino acid ABC transporter permease -
  GPW69_RS00350 ruvB 55957..56955 (+) 999 WP_029172061.1 Holliday junction branch migration DNA helicase RuvB -
  GPW69_RS00355 - 56955..57701 (+) 747 WP_074391036.1 GNAT family N-acetyltransferase -
  GPW69_RS00360 - 57703..58326 (+) 624 WP_074391037.1 HAD-IA family hydrolase -
  GPW69_RS00365 comR 58431..59330 (+) 900 WP_074391038.1 helix-turn-helix domain-containing protein Regulator
  GPW69_RS00370 - 59538..60758 (+) 1221 WP_074391039.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  GPW69_RS00380 - 60949..62472 (+) 1524 WP_074391040.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35117.03 Da        Isoelectric Point: 4.5433

>NTDB_id=1129574 GPW69_RS00365 WP_074391038.1 58431..59330(+) (comR) [Streptococcus suis isolate 9401240]
MNDKEFGQRVRQLRETASLTREQFCGDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKVAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQLT
QDFQKKPIVSVLKWKYALFVNKDRGEAEKHYLDAMLFAKLIENRELEEKIEEDWKVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=1129574 GPW69_RS00365 WP_074391038.1 58431..59330(+) (comR) [Streptococcus suis isolate 9401240]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGGTGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTGCCAGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGATTATTATGATGACTTGCCTGAGGAGGAGAAAGTAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTTCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTATCCAGTAGTGACTCAGAGATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTATGAACCAATACCAAAGATATTCGACAGTGTAGATAAAATTATACAGTTAACG
CAAGATTTTCAGAAAAAGCCAATTGTCAGCGTGTTGAAATGGAAGTACGCACTTTTTGTAAATAAGGATAGAGGTGAGGC
TGAAAAGCATTATCTAGATGCGATGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAGGAGAAGATTGAAGAAGATT
GGAAAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

91.639

100

0.916
  comR Streptococcus suis 05ZYH33

91.639

100

0.916
  comR Streptococcus suis D9

59.801

100

0.602
  comR Streptococcus mutans UA159

45.485

100

0.455
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.144

97.324

0.371

Multiple sequence alignment