Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GPW68_RS09560 Genome accession   NZ_LR738723
Coordinates   1906840..1907562 (-) Length   240 a.a.
NCBI ID   WP_012775334.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0088     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1901840..1912562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS09545 sufD 1903066..1904328 (-) 1263 WP_012775333.1 Fe-S cluster assembly protein SufD -
  GPW68_RS09550 sufC 1904345..1905118 (-) 774 WP_074389527.1 Fe-S cluster assembly ATPase SufC -
  GPW68_RS09555 - 1905671..1906843 (-) 1173 WP_012027769.1 glycosyltransferase family 4 protein -
  GPW68_RS09560 mecA 1906840..1907562 (-) 723 WP_012775334.1 adaptor protein MecA Regulator
  GPW68_RS09565 - 1907690..1908526 (-) 837 WP_012027770.1 undecaprenyl-diphosphate phosphatase -
  GPW68_RS09570 - 1908771..1910492 (-) 1722 WP_074389404.1 IS1634 family transposase -
  GPW68_RS09575 - 1910710..1912275 (+) 1566 WP_024405930.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28000.54 Da        Isoelectric Point: 4.0497

>NTDB_id=1129566 GPW68_RS09560 WP_012775334.1 1906840..1907562(-) (mecA) [Streptococcus suis isolate GD-0088]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=1129566 GPW68_RS09560 WP_012775334.1 1906840..1907562(-) (mecA) [Streptococcus suis isolate GD-0088]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTTTACACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCTGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACAGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATTGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment