Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GPW68_RS02790 Genome accession   NZ_LR738723
Coordinates   521112..523262 (+) Length   716 a.a.
NCBI ID   WP_074389179.1    Uniprot ID   A0AAP6DXW3
Organism   Streptococcus suis isolate GD-0088     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 516112..528262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS02765 - 517827..518420 (+) 594 WP_074389176.1 PBECR4 domain-containing protein -
  GPW68_RS02770 - 518665..518822 (+) 158 Protein_481 putative cross-wall-targeting lipoprotein signal domain-containing proteiin -
  GPW68_RS02775 - 519013..520329 (+) 1317 WP_074389177.1 glycosyltransferase family 2 protein -
  GPW68_RS02780 - 520358..520630 (+) 273 WP_074389178.1 DUF3884 family protein -
  GPW68_RS02785 - 520719..520910 (+) 192 WP_024381035.1 hypothetical protein -
  GPW68_RS02790 comA 521112..523262 (+) 2151 WP_074389179.1 peptide cleavage/export ABC transporter Regulator
  GPW68_RS02795 - 523284..523439 (+) 156 WP_000794567.1 hypothetical protein -
  GPW68_RS02800 - 523899..524768 (+) 870 WP_226319201.1 GHKL domain-containing protein -
  GPW68_RS02805 - 524783..525532 (+) 750 WP_074389180.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  GPW68_RS02810 - 525873..526253 (+) 381 Protein_489 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 81557.43 Da        Isoelectric Point: 6.6052

>NTDB_id=1129543 GPW68_RS02790 WP_074389179.1 521112..523262(+) (comA) [Streptococcus suis isolate GD-0088]
MKFSKRHYRAQVDSKDCGVAALAMVLEYYNSHYSLAELREMLGTTENGTTAFSIVSVANELGFDTEAIYADISLFDIEDI
KFPFIVHINKNNKFYHYYVIIGSDKKYIYIADPDPLIKLSKLTKEQFLSEWRGITILLKPNHEYKIKIKKTSFPSLLTLL
FNQKKLIFLIILLTLAVNFINIIGSYYLKRVIDSYIPKGELDFLNIMSISLIVIYLMQQFFVFGQGVLITVLSQILSKNI
MLSYIAHLFKLPLSFFATRRTGDIVSRFSDANIIIEVLSSLILSVILDVSIVTGVSIVLFLQSSYLFFIIIIAFPIYALV
IFLFMKPFRRSKTSVMEAGASLSSVLIEDINGIETIKSLTSEVDRYKIIKEEFSNYFKKITFYSRMELFQDVLKNFTQLL
FNVLILWQGAILVIEGKISLGSLITFNTLELYFLNSLENIINLQPKFQSASVAYNRLEEIYSVQSEFQDKFFITNFKLNS
SKIVISNLTYKYGYNQPLLKNINLVIEEGCKIAFVGLSGSGKTTLAKMLVNFMPPTYGSIEFGGININDIDKKTLRQLIN
YIPQKPYIFNGTILDNLLLGVEDEISFEEINKATEIAEIKSVIENLPLGYETELSTEHSILSGGQLQRVAIARALLTNPS
VLILDESTSNLDNLTERKIIDNLMSLDITVIFIAHRLNITEQVERIFVIENGMIIENGNHEDLILKQGFYSKILKG

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=1129543 GPW68_RS02790 WP_074389179.1 521112..523262(+) (comA) [Streptococcus suis isolate GD-0088]
ATGAAATTTTCGAAACGTCATTATCGTGCTCAAGTTGATTCAAAAGATTGTGGAGTAGCTGCTTTGGCCATGGTGTTAGA
ATACTATAATTCACATTATTCTTTAGCAGAACTTAGAGAAATGTTAGGTACAACTGAAAATGGGACTACTGCATTTAGTA
TAGTTTCTGTAGCAAATGAATTAGGGTTCGATACTGAAGCTATTTATGCAGATATTTCTTTATTTGACATAGAGGATATA
AAATTTCCATTTATTGTACACATAAATAAGAATAATAAATTTTATCATTACTATGTTATTATTGGCAGTGATAAAAAATA
TATTTATATAGCTGATCCTGATCCTCTGATAAAATTATCTAAACTAACTAAAGAACAGTTTCTTTCAGAATGGAGAGGGA
TAACTATATTATTAAAACCAAACCATGAGTACAAAATTAAAATAAAGAAGACAAGTTTTCCTTCTTTATTAACTTTACTG
TTTAATCAAAAGAAATTAATTTTTTTAATTATATTATTAACTTTAGCAGTAAACTTTATAAATATAATTGGTTCATACTA
TTTAAAGAGAGTAATTGATTCTTATATTCCTAAAGGGGAGCTGGATTTTCTTAATATAATGTCAATAAGCCTAATTGTTA
TTTATCTTATGCAACAGTTTTTTGTATTTGGTCAAGGGGTATTGATAACAGTTCTAAGTCAAATACTTTCAAAAAATATA
ATGCTGTCATATATTGCTCACCTTTTTAAACTTCCTCTATCTTTTTTTGCAACAAGAAGAACTGGCGATATTGTCTCTAG
ATTTTCAGATGCTAATATCATAATTGAAGTATTATCTAGTTTAATTTTATCTGTAATACTAGATGTGTCAATAGTTACTG
GAGTATCAATTGTACTTTTTTTGCAAAGTAGTTATTTATTTTTTATTATAATTATTGCGTTTCCAATTTATGCTTTAGTA
ATTTTTTTATTCATGAAACCATTTAGACGTAGTAAAACTAGTGTAATGGAAGCAGGAGCTTCACTTTCCTCAGTTCTTAT
AGAAGATATAAATGGAATAGAGACAATAAAATCTCTTACTAGTGAGGTTGATCGCTATAAAATTATAAAAGAGGAATTTA
GTAATTATTTTAAAAAAATTACTTTTTATAGTAGAATGGAGTTGTTTCAAGATGTGTTAAAAAATTTTACTCAATTGTTG
TTTAATGTATTAATTTTATGGCAAGGTGCTATTTTAGTAATTGAAGGAAAAATATCATTGGGATCTTTGATAACCTTTAA
TACTTTAGAACTTTATTTTCTGAATTCACTGGAGAACATTATTAATTTACAACCTAAATTTCAATCAGCAAGTGTTGCGT
ATAATAGATTAGAAGAAATCTATTCAGTTCAATCGGAATTTCAGGATAAGTTCTTCATAACAAATTTTAAATTGAATTCT
AGTAAGATAGTAATTTCAAATTTAACCTACAAATATGGCTATAACCAGCCTCTATTAAAAAATATTAATTTAGTTATCGA
GGAAGGTTGTAAAATAGCATTTGTTGGTCTTTCTGGTTCAGGGAAAACAACTCTAGCAAAAATGTTAGTCAATTTTATGC
CTCCTACCTATGGAAGTATTGAATTTGGAGGAATTAATATTAATGATATTGATAAGAAGACTTTGAGACAATTGATTAAT
TATATACCCCAGAAACCTTATATTTTTAACGGTACTATATTAGATAATCTTTTATTAGGTGTTGAAGATGAAATTTCATT
TGAAGAGATTAATAAAGCTACTGAGATTGCCGAGATAAAATCTGTTATAGAGAATTTACCGTTAGGATATGAGACCGAAC
TTTCCACTGAACATAGCATTTTGTCAGGAGGTCAACTTCAGAGAGTTGCTATTGCACGTGCATTATTAACCAATCCTTCG
GTATTAATCTTAGATGAGTCAACAAGTAATTTGGATAATTTAACGGAAAGAAAAATTATTGATAATTTAATGAGCTTAGA
TATAACTGTAATATTTATTGCTCACCGTCTTAATATAACAGAACAGGTTGAAAGGATATTTGTCATAGAAAATGGTATGA
TAATCGAAAACGGAAATCATGAAGATTTGATATTAAAACAAGGGTTTTATTCTAAAATATTAAAAGGTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-649)

ABC transporter transmembrane region (ABC_membrane)

(167-437)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

56.084

99.86

0.56
  comA Streptococcus gordonii str. Challis substr. CH1

56.084

99.86

0.56
  comA Streptococcus mitis SK321

55.524

99.86

0.554
  comA Streptococcus pneumoniae R6

55.245

99.86

0.552
  comA Streptococcus pneumoniae Rx1

55.245

99.86

0.552
  comA Streptococcus pneumoniae D39

55.245

99.86

0.552
  comA Streptococcus pneumoniae TIGR4

54.965

99.86

0.549
  comA/nlmT Streptococcus mutans UA159

49.017

99.441

0.487

Multiple sequence alignment