Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GPW51_RS08725 Genome accession   NZ_LR738721
Coordinates   1723223..1723945 (-) Length   240 a.a.
NCBI ID   WP_012775334.1    Uniprot ID   -
Organism   Streptococcus suis isolate S10     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1718223..1728945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW51_RS08710 sufD 1719449..1720711 (-) 1263 WP_012775333.1 Fe-S cluster assembly protein SufD -
  GPW51_RS08715 sufC 1720728..1721501 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  GPW51_RS08720 - 1722054..1723226 (-) 1173 WP_012027769.1 glycosyltransferase family 4 protein -
  GPW51_RS08725 mecA 1723223..1723945 (-) 723 WP_012775334.1 adaptor protein MecA Regulator
  GPW51_RS08730 - 1724073..1724909 (-) 837 WP_012027770.1 undecaprenyl-diphosphate phosphatase -
  GPW51_RS08735 - 1725036..1726601 (+) 1566 WP_012028491.1 ABC transporter substrate-binding protein/permease -
  GPW51_RS08740 - 1726594..1727337 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  GPW51_RS08745 - 1727463..1727672 (-) 210 WP_009910800.1 hypothetical protein -
  GPW51_RS08750 - 1727758..1728660 (-) 903 WP_012027774.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28000.54 Da        Isoelectric Point: 4.0497

>NTDB_id=1129459 GPW51_RS08725 WP_012775334.1 1723223..1723945(-) (mecA) [Streptococcus suis isolate S10]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=1129459 GPW51_RS08725 WP_012775334.1 1723223..1723945(-) (mecA) [Streptococcus suis isolate S10]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTTTACACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCTGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACAGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATTGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment