Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   FQT45_RS08065 Genome accession   NZ_LR595858
Coordinates   1646685..1648613 (-) Length   642 a.a.
NCBI ID   WP_077323445.1    Uniprot ID   -
Organism   Streptococcus pseudoporcinus strain NCTC10228     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641685..1653613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT45_RS08040 (NCTC10228_01655) - 1642454..1642807 (-) 354 WP_007892969.1 S1 RNA-binding domain-containing protein -
  FQT45_RS08045 (NCTC10228_01656) - 1642807..1644207 (-) 1401 WP_077323442.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FQT45_RS08050 (NCTC10228_01657) - 1644241..1644882 (-) 642 WP_007892962.1 response regulator transcription factor -
  FQT45_RS08055 (NCTC10228_01658) - 1644875..1645879 (-) 1005 WP_077323443.1 sensor histidine kinase -
  FQT45_RS08060 (NCTC10228_01659) liaF 1645876..1646571 (-) 696 WP_077323444.1 cell wall-active antibiotics response protein LiaF -
  FQT45_RS08065 (NCTC10228_01660) pknB 1646685..1648613 (-) 1929 WP_077323445.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FQT45_RS08070 (NCTC10228_01661) - 1648610..1649350 (-) 741 WP_077323446.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FQT45_RS08075 (NCTC10228_01662) rsmB 1649389..1650711 (-) 1323 WP_077323447.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FQT45_RS08080 (NCTC10228_01663) fmt 1650704..1651636 (-) 933 WP_077323448.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 642 a.a.        Molecular weight: 70078.50 Da        Isoelectric Point: 8.9722

>NTDB_id=1128496 FQT45_RS08065 WP_077323445.1 1646685..1648613(-) (pknB) [Streptococcus pseudoporcinus strain NCTC10228]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKFIQDNAPLTNNQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGTKATIQSDIYAMGIMLYEMLTGHIPYDGDSAVTIALQHFQKPLPSIVDENPSVP
QALENVVIKATAKKLSDRYATTFEMSRDLMTALSYNRSREKKLIFDDGENTRPLPKVTPTPNTNPKTSPKEPIASTKALQ
ASEQLKKPKKEKKRGRFLGTLFKILFALFVVGVAIFTFLILTKPSNVKVPNLSGRDLQTAKADLQALGLKVGNVEQAPSN
DVSEGKVIETNPIAGTTKREGSKVDILVSKGSSGFKVKDYVGDDYQKAMEDLMTTYGLKRKQISIKRVIKDDYNKQDIVL
SQTPNKGYFNPNGKTKFTLTVATTEIIGMPQLIGMTYKDAKLLLEEKGIDLNRVKVYQMNPDGTTTPVEPNSDTLIAYQN
PLLNGQVSLTDTGEISLYINSDSQHVPSSSSSSSSSTETSSESSTSSSSSSSNSSSESSSGSSSTSTSTSTSTSTTSSNT
VQ

Nucleotide


Download         Length: 1929 bp        

>NTDB_id=1128496 FQT45_RS08065 WP_077323445.1 1646685..1648613(-) (pknB) [Streptococcus pseudoporcinus strain NCTC10228]
ATGATACAGATTGGCAAATTATTTGCTGGTCGATATCGCATATTAAAATCTATTGGCCGTGGAGGCATGGCAGATGTTTA
TTTAGCTAATGACTTGATTCTAGATAATGAAGACGTGGCAATAAAGGTATTGCGTACTAATTATCAAACGGATCAAGTTG
CTGTCGCACGTTTCCAAAGGGAAGCAAGAGCGATGGCTGAGCTGAATCATCCTAATATCGTAGCTATTAGAGATATAGGC
GAAGAAGACGGGCAGCAATTTTTAGTAATGGAATATGTTGATGGTGCTGATCTTAAAAAGTTCATTCAAGATAATGCACC
TCTGACTAATAATCAAGTCGTTCGGATTATGGAAGAGGTTTTGTCAGCAATGACTTTAGCCCATCAAAAAGGAATTGTCC
ATAGGGATTTAAAGCCGCAGAACATTCTTTTAACTAAAGAAGGTGTTGTCAAAGTTACAGACTTTGGTATTGCTGTTGCT
TTTGCCGAAACCAGCTTAACACAGACTAATTCCATGTTAGGAAGTGTTCATTATTTATCGCCTGAGCAGGCACGTGGCAC
AAAAGCAACCATCCAAAGTGATATCTATGCAATGGGAATCATGCTATATGAAATGTTAACGGGTCACATTCCCTATGATG
GGGATAGTGCGGTAACGATTGCTTTGCAACATTTCCAAAAGCCACTCCCTTCCATTGTGGATGAGAATCCCAGTGTGCCA
CAAGCTTTAGAAAATGTTGTTATTAAAGCTACTGCTAAAAAATTGAGTGACCGTTATGCAACAACTTTTGAGATGAGCAG
AGATTTAATGACAGCCTTGAGTTATAACCGTAGTCGTGAAAAGAAGTTGATTTTTGATGACGGTGAGAACACAAGACCTT
TGCCCAAAGTGACGCCTACGCCTAATACCAACCCTAAAACAAGCCCTAAGGAACCAATAGCTTCTACTAAAGCACTGCAA
GCTTCAGAGCAGCTTAAAAAGCCGAAAAAAGAGAAAAAACGAGGACGTTTCTTAGGAACACTTTTCAAAATTTTATTTGC
TTTATTTGTGGTTGGTGTAGCTATCTTTACTTTCTTAATTTTAACCAAACCTTCTAATGTTAAAGTTCCTAACCTAAGTG
GTAGAGATTTACAGACTGCCAAAGCAGATTTGCAAGCCCTAGGTTTAAAAGTCGGCAATGTTGAGCAGGCACCAAGCAAT
GATGTTTCAGAAGGGAAAGTTATTGAAACGAATCCGATCGCAGGAACAACAAAGCGTGAAGGGTCTAAAGTAGATATTTT
AGTTTCCAAAGGAAGCAGCGGCTTTAAAGTCAAGGATTACGTAGGTGATGATTACCAAAAAGCTATGGAAGATTTAATGA
CTACCTACGGCTTAAAACGTAAACAAATAAGTATCAAACGCGTCATAAAAGATGACTATAATAAGCAAGACATTGTCTTG
AGCCAGACTCCAAATAAGGGCTACTTTAACCCAAATGGGAAAACAAAGTTCACTTTAACGGTTGCAACTACAGAAATAAT
TGGGATGCCGCAACTTATTGGAATGACTTACAAAGATGCTAAACTCTTGCTTGAAGAGAAAGGGATTGATTTAAATCGTG
TTAAAGTTTATCAGATGAATCCGGATGGTACTACGACACCGGTTGAACCAAACTCTGATACCTTAATAGCTTATCAAAAT
CCTCTCCTTAATGGGCAGGTTTCACTGACGGATACAGGAGAAATTAGTCTCTATATTAATAGTGACAGCCAACATGTTCC
TTCGTCAAGTAGTTCAAGTTCATCAAGTACAGAGACTAGCTCTGAGTCTAGCACTAGTTCAAGTTCTTCCAGTTCAAACT
CCTCTTCGGAGTCAAGTTCTGGATCTAGCTCAACTAGTACTTCAACGAGTACCTCGACATCCACAACGAGTTCAAATACA
GTTCAGTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-233)

PASTA domain (PASTA)

(367-430)

PASTA domain (PASTA)

(509-580)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

61.84

91.433

0.565
  stkP/pknB Streptococcus salivarius strain HSISS4

60.304

92.212

0.556
  stkP Streptococcus pneumoniae TIGR4

60.889

70.093

0.427
  stkP Streptococcus pneumoniae D39

60.444

70.093

0.424
  stkP Streptococcus pneumoniae R6

60.444

70.093

0.424
  stkP Streptococcus pneumoniae Rx1

60.222

70.093

0.422

Multiple sequence alignment