Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FQT45_RS02115 Genome accession   NZ_LR595858
Coordinates   390172..390927 (+) Length   251 a.a.
NCBI ID   WP_077322886.1    Uniprot ID   A0A4U9XI46
Organism   Streptococcus pseudoporcinus strain NCTC10228     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 385172..395927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT45_RS02100 (NCTC10228_00422) - 385430..387001 (-) 1572 WP_077322888.1 ABC transporter substrate-binding protein/permease -
  FQT45_RS02105 (NCTC10228_00423) - 387190..389094 (+) 1905 WP_077322887.1 DUF2207 domain-containing protein -
  FQT45_RS02110 (NCTC10228_00424) - 389219..390058 (+) 840 WP_007893599.1 undecaprenyl-diphosphate phosphatase -
  FQT45_RS02115 (NCTC10228_00425) mecA 390172..390927 (+) 756 WP_077322886.1 adaptor protein MecA Regulator
  FQT45_RS02120 (NCTC10228_00426) - 390934..392088 (+) 1155 WP_077322885.1 glycosyltransferase family 4 protein -
  FQT45_RS02125 (NCTC10228_00427) sufC 392214..392984 (+) 771 WP_077322884.1 Fe-S cluster assembly ATPase SufC -
  FQT45_RS02130 (NCTC10228_00428) sufD 393079..394344 (+) 1266 WP_077322883.1 Fe-S cluster assembly protein SufD -
  FQT45_RS02135 (NCTC10228_00429) - 394360..395586 (+) 1227 WP_077322882.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29333.28 Da        Isoelectric Point: 4.1854

>NTDB_id=1128468 FQT45_RS02115 WP_077322886.1 390172..390927(+) (mecA) [Streptococcus pseudoporcinus strain NCTC10228]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKEIDFEDLTDLGDVSQMTPEDFFKTIEKNMIEKGDVNAHEKLEKIEEMLEEAVEANQTQTTVSDKTTQTVEPMDYVHYV
FDFLTIEEVISFSKIVNFPIEASELYKETNRYHLTILLDIQNQPAYFANIMYARLIEHALPGSRTRAYLQEHATLLIEDQ
AVEQLKKIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1128468 FQT45_RS02115 WP_077322886.1 390172..390927(+) (mecA) [Streptococcus pseudoporcinus strain NCTC10228]
ATGGAAATGAAACAAATTAGTGAAACGACACTAAAGATAACAATCAGTATGGATGATTTGGAAGAAAGAGGCATGGAATT
AAAGGATTTTTTAATTCCTCAGGAAAAAACAGAAGAATTTTTCTACACTGTTATGGATGAACTGGATTTACCTGAAAACT
TTAAAGATAGTGGGATGTTAAGTTTTAGGGTTACCCCACGTAAAGATCGTTTAGATGTTTTTGTTACGAAGTCAGAATTA
TCTAAAGAAATTGATTTTGAGGATTTGACTGATCTAGGAGATGTTTCTCAGATGACGCCCGAAGATTTTTTTAAAACAAT
TGAAAAAAATATGATCGAAAAAGGCGATGTCAACGCTCATGAAAAATTAGAAAAAATTGAAGAAATGTTAGAAGAGGCAG
TTGAGGCAAATCAAACTCAAACGACAGTGAGTGATAAAACTACCCAGACTGTTGAACCGATGGACTACGTCCATTATGTT
TTTGATTTTTTAACTATAGAAGAAGTCATTAGCTTTTCTAAAATAGTCAACTTTCCAATTGAAGCCTCAGAGCTTTACAA
GGAAACGAATCGTTATCACCTGACAATCTTACTTGATATTCAAAATCAGCCAGCCTACTTTGCTAATATTATGTACGCCC
GTTTAATTGAACATGCATTACCTGGTTCAAGAACACGTGCTTATTTGCAGGAGCATGCAACCTTACTGATCGAAGATCAA
GCAGTAGAACAGCTGAAAAAGATTGAATTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9XI46

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

61.29

98.805

0.606
  mecA Streptococcus thermophilus LMD-9

56.68

98.406

0.558
  mecA Streptococcus thermophilus LMG 18311

56.275

98.406

0.554
  mecA Streptococcus pneumoniae TIGR4

45.817

100

0.458
  mecA Streptococcus pneumoniae Rx1

45.418

100

0.454
  mecA Streptococcus pneumoniae D39

45.418

100

0.454
  mecA Streptococcus pneumoniae R6

45.418

100

0.454

Multiple sequence alignment