Detailed information NTG1128459

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FQT45_RS00315
• Genome accession: NZ_LR595858
• Coordinates: 46265..47170 (+)
• Length: 301 a.a.
• NCBI ID: WP_077323318.1
• Uniprot ID: A0A4U9XJ30
• Organism: Streptococcus pseudoporcinus strain NCTC10228
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 41265..52170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FQT45_RS00295 (NCTC10228_00059)	-	41424..42515 (-)	1092	WP_077323314.1	CHAP domain-containing protein	-
FQT45_RS00300 (NCTC10228_00060)	-	42635..43252 (-)	618	WP_077323315.1	hypothetical protein	-
FQT45_RS00305 (NCTC10228_00061)	-	44274..44822 (+)	549	WP_223837127.1	GNAT family N-acetyltransferase	-
FQT45_RS00310 (NCTC10228_00062)	purB	44870..46162 (+)	1293	WP_077323317.1	adenylosuccinate lyase	-
FQT45_RS00315 (NCTC10228_00063)	comR	46265..47170 (+)	906	WP_077323318.1	helix-turn-helix transcriptional regulator	Regulator
FQT45_RS10570 (NCTC10228_00064)	-	47243..47338 (+)	96	WP_199286071.1	quorum-sensing system DWW-type pheromone	-
FQT45_RS00320 (NCTC10228_00065)	ruvB	47373..48371 (+)	999	WP_007891873.1	Holliday junction branch migration DNA helicase RuvB	-
FQT45_RS00325 (NCTC10228_00066)	-	48839..49282 (+)	444	WP_077323319.1	low molecular weight protein-tyrosine-phosphatase	-
FQT45_RS00330 (NCTC10228_00067)	-	49291..49692 (+)	402	WP_007891657.1	membrane protein	-
FQT45_RS00335 (NCTC10228_00068)	-	49689..51467 (+)	1779	WP_077323320.1	acyltransferase family protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35841.73 Da
• Isoelectric Point: 8.1593

>NTDB_id=1128459 FQT45_RS00315 WP_077323318.1 46265..47170(+) (comR) [Streptococcus pseudoporcinus strain NCTC10228]
MKKLGKKIQKLRLDKSLTRETICGDESELSIRQLARIEKGQSIPSLSKVLFIAKKLDLPVIELINPECLVLPKRYKELKY
LILRRPTYMNNQNLVDREAQFDEIFEDYYATLPEEEQLIIDLLQSRFDVYQSGDTNYGKELLCEYISQIRKKKSYALNDI
FLIDLYLTCGIVSNFKEELFDKGNFDCFTNKLVLLEDKLELKDLFLLNNVLLTSIAVGISIKEYQKTRILLDVCRRIMTI
TQDFQRMPIYYMYEWKYTLFYMKDSQKAYYYYRQSLIFARTLTDSYLVNRLKTSWELDNQS

Nucleotide

• Length: 906 bp

>NTDB_id=1128459 FQT45_RS00315 WP_077323318.1 46265..47170(+) (comR) [Streptococcus pseudoporcinus strain NCTC10228]
ATGAAAAAACTTGGGAAAAAGATTCAAAAATTGAGGTTAGACAAGAGCCTGACTCGTGAAACGATTTGTGGAGATGAGTC
AGAATTATCAATTCGACAGCTAGCTCGTATTGAAAAAGGGCAATCTATTCCTAGTTTATCTAAAGTCTTATTTATTGCAA
AAAAATTAGATTTACCTGTTATTGAACTTATTAATCCAGAGTGTTTGGTTTTACCAAAACGTTATAAGGAACTTAAATAT
CTGATTCTTAGGCGACCAACCTACATGAATAATCAAAATTTAGTGGATCGCGAAGCTCAGTTTGATGAAATATTTGAAGA
TTATTACGCGACTTTACCTGAAGAAGAGCAGCTAATTATTGATTTATTACAGTCTCGGTTTGATGTCTACCAAAGTGGTG
ATACTAATTATGGTAAAGAATTACTCTGTGAGTATATCAGCCAAATTCGTAAGAAAAAGAGTTACGCTTTAAATGATATT
TTTTTAATCGATCTTTACTTAACTTGTGGAATAGTTTCAAATTTCAAAGAAGAATTATTTGATAAGGGAAATTTTGATTG
TTTTACTAATAAATTAGTCCTTTTGGAAGATAAGTTAGAGTTAAAAGATCTCTTTTTACTAAACAACGTCCTTCTCACTT
CCATTGCCGTAGGGATTAGTATTAAAGAATATCAGAAAACAAGGATACTTTTGGATGTTTGTCGACGGATTATGACGATT
ACCCAAGACTTTCAGCGTATGCCTATTTACTATATGTACGAATGGAAATACACTTTATTTTATATGAAGGACTCCCAAAA
GGCTTATTATTACTATCGTCAATCCTTAATATTTGCACGGACACTAACAGATAGTTATCTTGTTAATCGTTTAAAAACAA
GTTGGGAATTAGATAATCAATCGTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

3D structure

• AlphaFold DB: A0A4U9XJ30

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	50.336	99.003	0.498
comR	Streptococcus pyogenes MGAS8232	45.515	100	0.455
comR	Streptococcus mutans UA159	44.186	100	0.442
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	44.291	96.013	0.425
comR	Streptococcus suis P1/7	38.411	100	0.385
comR	Streptococcus suis 05ZYH33	38.411	100	0.385