Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FQT67_RS00355 Genome accession   NZ_LR595857
Coordinates   58613..59524 (+) Length   303 a.a.
NCBI ID   WP_012766420.1    Uniprot ID   -
Organism   Streptococcus sp. NCTC 11567 strain NCTC11567     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53613..64524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT67_RS00340 (NCTC11567_00070) purK 54043..55116 (+) 1074 WP_015016519.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  FQT67_RS00345 (NCTC11567_00071) - 55135..56994 (+) 1860 WP_143936354.1 DUF262 domain-containing protein -
  FQT67_RS00350 (NCTC11567_00072) purB 57179..58471 (+) 1293 WP_022554088.1 adenylosuccinate lyase -
  FQT67_RS00355 (NCTC11567_00073) comR 58613..59524 (+) 912 WP_012766420.1 XRE family transcriptional regulator Regulator
  FQT67_RS10855 (NCTC11567_00074) comS 59611..59706 (+) 96 WP_198455558.1 quorum-sensing system DWW-type pheromone Regulator
  FQT67_RS00360 (NCTC11567_00075) ruvB 59758..60756 (+) 999 WP_015057190.1 Holliday junction branch migration DNA helicase RuvB -
  FQT67_RS00365 (NCTC11567_00076) - 60891..61322 (+) 432 WP_003059365.1 low molecular weight protein-tyrosine-phosphatase -
  FQT67_RS00370 (NCTC11567_00077) - 61351..61752 (+) 402 WP_003049089.1 MORN repeat-containing protein -
  FQT67_RS00375 (NCTC11567_00078) - 61749..63524 (+) 1776 WP_003059359.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35726.31 Da        Isoelectric Point: 4.5798

>NTDB_id=1128399 FQT67_RS00355 WP_012766420.1 58613..59524(+) (comR) [Streptococcus sp. NCTC 11567 strain NCTC11567]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEQLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKLRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKIIIDISSLSIKTNKLDNLEKTIAISQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=1128399 FQT67_RS00355 WP_012766420.1 58613..59524(+) (comR) [Streptococcus sp. NCTC 11567 strain NCTC11567]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGTGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAACAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTAAGTG
AAAACATCAATTTTGGTGTCGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAACTACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAATTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGGCA
AAAATCCAGGATTGGAATAGAATGCCTATACTAAAATTAATAGAATGGAAGTACTTTTTAATAAAACAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAAATAACAGGAGACAAGTATTTGGAAGAGCAATTAATCA
AAGAATGGGAGAAAGATATTTGTGCTTATTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

82.178

100

0.822
  comR Streptococcus pyogenes MGAS315

54.667

99.01

0.541
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

50.847

97.36

0.495
  comR Streptococcus mutans UA159

49.498

98.68

0.488

Multiple sequence alignment