Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   FGL20_RS07525 Genome accession   NZ_LR594050
Coordinates   1517291..1519219 (-) Length   642 a.a.
NCBI ID   WP_003085655.1    Uniprot ID   A0A4V0HD21
Organism   Streptococcus porcinus strain NCTC10925     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1512291..1524219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL20_RS07500 (NCTC10925_01511) - 1513060..1513413 (-) 354 WP_003083428.1 S1 RNA-binding domain-containing protein -
  FGL20_RS07505 (NCTC10925_01512) - 1513413..1514813 (-) 1401 WP_003086028.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGL20_RS07510 (NCTC10925_01513) - 1514847..1515488 (-) 642 WP_003084661.1 response regulator transcription factor -
  FGL20_RS07515 (NCTC10925_01514) - 1515481..1516485 (-) 1005 WP_003085144.1 sensor histidine kinase -
  FGL20_RS07520 (NCTC10925_01515) liaF 1516482..1517177 (-) 696 WP_003082835.1 cell wall-active antibiotics response protein LiaF -
  FGL20_RS07525 (NCTC10925_01516) stkP/pknB 1517291..1519219 (-) 1929 WP_003085655.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FGL20_RS07530 (NCTC10925_01517) - 1519216..1519956 (-) 741 WP_093958944.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FGL20_RS07535 (NCTC10925_01518) rsmB 1519995..1521317 (-) 1323 WP_093958945.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FGL20_RS07540 (NCTC10925_01519) fmt 1521310..1522242 (-) 933 WP_093958946.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 642 a.a.        Molecular weight: 70014.51 Da        Isoelectric Point: 9.2826

>NTDB_id=1128056 FGL20_RS07525 WP_003085655.1 1517291..1519219(-) (stkP/pknB) [Streptococcus porcinus strain NCTC10925]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKFIQDNAPLTNNQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLYEMLTGHIPYDGDSAVTIALQHFQKPLPSIVDENPSVP
QALENVVIKATAKKLSDRYATTFEMSRDLMTALSYNRSREKKLIFDDGENTKPLPKVTPTLNTSPKSSPKVTTTPTKAAQ
TSEQLKKPKKEKKRGRFLGTLFKILFALFVVGVAIFTFLILTKPTNVKVPNLSGRDLQTAKADLQALGFKVGNVEQVPSD
EVAQGNVIETNPIAGTTKREGSKVDIIVSKGSSGFKVKDYVGDDYQKAMEDLMTTYGLKRKQIKIKRVIKDDYSKQDIVL
NQSPNKGYFNPNGKTKFTLSVATTEIIGMPQLIGMTYKNAKLLLEEKGIDLNRVKVYQMNPDGTMTPVNPSSDTLIAYQN
PLLGGQISLTDTGEISLYINSDSQHTPQSSSSSSSSTEASSESSTSSGSSTTNSSSESSSGSSSTSTSTSTSTSTTSSDP
SQ

Nucleotide


Download         Length: 1929 bp        

>NTDB_id=1128056 FGL20_RS07525 WP_003085655.1 1517291..1519219(-) (stkP/pknB) [Streptococcus porcinus strain NCTC10925]
ATGATACAGATTGGCAAATTATTTGCTGGTCGATATCGCATATTAAAATCTATTGGCCGTGGAGGCATGGCAGATGTTTA
TTTAGCTAATGACTTGATCTTAGATAATGAAGATGTGGCAATAAAGGTATTGCGGACGAATTATCAGACAGATCAAGTTG
CTGTTGCACGTTTCCAAAGGGAAGCAAGAGCAATGGCTGAGCTGAATCATCCTAATATCGTAGCTATTAGAGATATAGGC
GAAGAAGACGGGCAGCAATTTTTAGTAATGGAATATGTTGATGGCGCAGATCTTAAGAAGTTCATTCAAGATAACGCACC
TCTGACTAATAATCAAGTGGTTCGGATTATGGAAGAAGTCTTATCGGCAATGACTTTAGCCCATCAAAAAGGTATTGTTC
ATAGAGATTTAAAACCACAGAACATTCTTTTAACTAAAGAAGGTGTTGTCAAAGTCACAGACTTTGGTATCGCTGTTGCT
TTTGCGGAAACCAGCTTAACACAGACTAATTCCATGTTAGGGAGTGTTCATTATTTATCGCCTGAGCAGGCACGTGGTTC
AAAAGCAACTATTCAAAGTGACATCTATGCAATGGGAATTATGCTCTATGAAATGTTGACTGGTCATATTCCCTATGATG
GGGATAGTGCGGTAACGATTGCTTTGCAACATTTCCAAAAACCTCTTCCTTCAATTGTAGATGAGAATCCTAGTGTCCCC
CAAGCTTTAGAAAACGTTGTTATTAAAGCAACAGCTAAAAAGTTAAGTGACCGTTATGCAACGACTTTTGAAATGAGCAG
AGATTTAATGACAGCCTTGAGCTATAATCGTAGTCGTGAAAAGAAGTTGATTTTTGATGACGGTGAGAACACAAAACCTT
TGCCAAAAGTGACTCCTACGCTTAATACCAGTCCTAAATCAAGTCCTAAGGTAACAACCACTCCCACTAAAGCAGCACAG
ACTTCAGAACAGCTTAAAAAGCCTAAAAAAGAGAAAAAGAGAGGACGTTTCTTAGGAACTCTTTTCAAAATTTTATTTGC
TTTATTTGTGGTTGGTGTAGCCATCTTTACGTTCTTAATTTTAACAAAACCTACTAATGTTAAAGTTCCTAACTTAAGTG
GTAGAGATTTACAGACTGCAAAAGCAGATTTACAAGCGCTAGGTTTTAAAGTTGGGAATGTTGAACAAGTACCAAGTGAT
GAAGTTGCACAAGGAAATGTTATTGAAACGAATCCGATTGCAGGAACAACAAAACGTGAGGGTTCTAAGGTAGACATTAT
AGTTTCTAAAGGAAGTAGTGGCTTTAAAGTTAAGGATTATGTAGGTGACGATTATCAAAAGGCTATGGAAGACTTAATGA
CTACTTACGGTTTAAAACGTAAACAAATAAAAATTAAACGTGTTATAAAAGATGATTATAGCAAGCAAGATATTGTTTTA
AACCAATCACCAAATAAGGGCTACTTTAATCCCAACGGAAAAACGAAGTTTACCTTATCGGTTGCAACCACAGAAATAAT
TGGGATGCCACAACTCATTGGAATGACCTATAAGAATGCTAAACTCTTACTTGAAGAGAAGGGAATTGATTTAAATCGTG
TTAAGGTTTATCAGATGAATCCTGATGGTACTATGACACCGGTTAATCCAAGCTCTGATACACTAATTGCTTATCAAAAT
CCTCTACTTGGCGGGCAGATTTCGCTGACTGACACAGGAGAAATCAGTCTTTATATTAATAGTGATAGCCAACATACTCC
ACAATCAAGTAGTTCAAGTTCATCAAGTACAGAAGCTAGTTCTGAGTCTAGTACTAGTTCAGGTTCTTCCACCACCAATT
CATCCTCTGAGTCGAGCTCTGGATCCAGCTCAACCAGCACCTCAACCAGTACTAGCACATCTACAACCAGTTCGGATCCA
AGTCAATAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(367-430)

PASTA domain (PASTA)

(509-580)

Protein kinase domain (Pkinase)

(12-233)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0HD21

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

59.23

97.04

0.575
  pknB Streptococcus mutans UA159

63.122

90.81

0.573
  stkP Streptococcus pneumoniae TIGR4

60.652

71.651

0.435
  stkP Streptococcus pneumoniae D39

60.217

71.651

0.431
  stkP Streptococcus pneumoniae R6

60.217

71.651

0.431
  stkP Streptococcus pneumoniae Rx1

60

71.651

0.43

Multiple sequence alignment