Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL20_RS02050 Genome accession   NZ_LR594050
Coordinates   379874..380629 (+) Length   251 a.a.
NCBI ID   WP_093959213.1    Uniprot ID   A0A4V0H2K0
Organism   Streptococcus porcinus strain NCTC10925     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 374874..385629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL20_RS02035 (NCTC10925_00411) - 375129..376700 (-) 1572 WP_093959210.1 ABC transporter substrate-binding protein/permease -
  FGL20_RS02040 (NCTC10925_00412) - 376890..378794 (+) 1905 WP_093959211.1 DUF2207 domain-containing protein -
  FGL20_RS02045 (NCTC10925_00413) - 378919..379758 (+) 840 WP_093959212.1 undecaprenyl-diphosphate phosphatase -
  FGL20_RS02050 (NCTC10925_00414) mecA 379874..380629 (+) 756 WP_093959213.1 adaptor protein MecA Regulator
  FGL20_RS02055 (NCTC10925_00415) - 380636..381790 (+) 1155 WP_093959214.1 glycosyltransferase family 4 protein -
  FGL20_RS02060 (NCTC10925_00416) sufC 381916..382686 (+) 771 WP_003083205.1 Fe-S cluster assembly ATPase SufC -
  FGL20_RS02065 (NCTC10925_00417) sufD 382780..384045 (+) 1266 WP_093959215.1 Fe-S cluster assembly protein SufD -
  FGL20_RS02070 (NCTC10925_00418) - 384060..385286 (+) 1227 WP_093959216.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29159.12 Da        Isoelectric Point: 4.1347

>NTDB_id=1128027 FGL20_RS02050 WP_093959213.1 379874..380629(+) (mecA) [Streptococcus porcinus strain NCTC10925]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKEIDFEDLTDLGDVSQMTPEDFFKTIEKSMIEKGDVNAHEKLEKIEEMLEEAVEASQSQTTAADEPAQIVEPMDYVHYV
FDFLTIEEVISFSKIVNFPIEASELYKETSRYHLTILLDIQNQPAYFANIMYARLIEHALPGSKTRAYLQEHATLLIEDQ
AIEQLKKIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1128027 FGL20_RS02050 WP_093959213.1 379874..380629(+) (mecA) [Streptococcus porcinus strain NCTC10925]
ATGGAAATGAAACAAATTAGTGAAACAACACTAAAAATAACGATTAGCATGGATGATTTAGAAGAAAGAGGAATGGAATT
GAAAGATTTCTTGATTCCTCAGGAAAAAACAGAAGAATTCTTCTATACCGTTATGGATGAGTTGGATTTACCTGAAAACT
TTAAAGATAGTGGGATGTTGAGTTTCAGAGTTACCCCACGTAAAGATCGTTTAGATGTTTTTGTTACTAAGTCAGAATTA
TCTAAAGAAATTGATTTTGAAGATTTAACTGATTTAGGAGATGTTTCTCAGATGACACCCGAAGATTTTTTTAAAACAAT
TGAAAAAAGCATGATAGAAAAAGGCGATGTCAATGCCCATGAAAAATTGGAAAAAATTGAAGAAATGTTAGAAGAAGCAG
TTGAGGCAAGCCAATCTCAAACTACAGCAGCTGATGAACCTGCTCAGATTGTTGAACCAATGGACTATGTTCATTATGTT
TTTGATTTCCTAACGATAGAGGAAGTCATTAGCTTTTCTAAGATAGTCAACTTTCCAATTGAAGCTTCGGAGCTTTACAA
GGAAACTAGTCGCTATCATCTGACAATCTTACTTGATATTCAAAATCAGCCAGCCTACTTTGCTAATATTATGTATGCTA
GGTTAATTGAACATGCACTACCTGGTTCAAAAACACGTGCTTATTTGCAAGAACATGCAACCTTACTCATTGAAGATCAA
GCAATAGAGCAGTTGAAAAAGATTGAATTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H2K0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

61.694

98.805

0.61
  mecA Streptococcus thermophilus LMD-9

56.68

98.406

0.558
  mecA Streptococcus thermophilus LMG 18311

56.275

98.406

0.554
  mecA Streptococcus pneumoniae TIGR4

45.817

100

0.458
  mecA Streptococcus pneumoniae Rx1

45.418

100

0.454
  mecA Streptococcus pneumoniae D39

45.418

100

0.454
  mecA Streptococcus pneumoniae R6

45.418

100

0.454

Multiple sequence alignment