Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FGL20_RS00305 Genome accession   NZ_LR594050
Coordinates   43711..44616 (+) Length   301 a.a.
NCBI ID   WP_003083020.1    Uniprot ID   A0A4V0GXT6
Organism   Streptococcus porcinus strain NCTC10925     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 38711..49616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL20_RS00290 (NCTC10925_00058) - 39103..40146 (-) 1044 WP_093959243.1 CHAP domain-containing protein -
  FGL20_RS00295 (NCTC10925_00059) - 40267..40884 (-) 618 WP_093959242.1 hypothetical protein -
  FGL20_RS00300 (NCTC10925_00060) purB 42314..43606 (+) 1293 WP_093959241.1 adenylosuccinate lyase -
  FGL20_RS00305 (NCTC10925_00061) comR 43711..44616 (+) 906 WP_003083020.1 helix-turn-helix transcriptional regulator Regulator
  FGL20_RS09695 (NCTC10925_00062) - 44689..44787 (+) 99 WP_198920371.1 quorum-sensing system DWW-type pheromone -
  FGL20_RS00310 (NCTC10925_00063) ruvB 44819..45817 (+) 999 WP_003085189.1 Holliday junction branch migration DNA helicase RuvB -
  FGL20_RS00315 (NCTC10925_00064) - 46093..46536 (+) 444 WP_093959240.1 low molecular weight protein-tyrosine-phosphatase -
  FGL20_RS00320 (NCTC10925_00065) - 46545..46946 (+) 402 WP_093959239.1 hypothetical protein -
  FGL20_RS00325 (NCTC10925_00066) - 46943..48721 (+) 1779 WP_093959238.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 301 a.a.        Molecular weight: 35865.80 Da        Isoelectric Point: 8.6936

>NTDB_id=1128017 FGL20_RS00305 WP_003083020.1 43711..44616(+) (comR) [Streptococcus porcinus strain NCTC10925]
MKKLGKKIQKLRLDKSLTRETICGDESELSIRQLARIEKGQSIPSLAKVLFIAKKLELPVVELINPECLVLPKRYKELKY
LILRRPTYMNGQNLVDREAQFDEIFEDYYATLPEEEQLIIDLLQSRFDVYQSGDTNYGKELLREYISQIRKKKSYALNDI
FLIDLYLTCGMVSNFKEELFDKGNFDCFTNKLVLLEDKLELKDLFLLNNVLLTSIAVGISIKEYQKTRILLNVCRRIMTI
TQDFQRMPIYYMYEWKYTLFYMKDSQKAYYYYRQSLIFARTLTDNYLVNRLKTSWELDNQS

Nucleotide


Download         Length: 906 bp        

>NTDB_id=1128017 FGL20_RS00305 WP_003083020.1 43711..44616(+) (comR) [Streptococcus porcinus strain NCTC10925]
ATGAAAAAACTTGGGAAAAAGATTCAAAAATTGAGGTTGGATAAGAGTCTGACTCGTGAAACTATTTGTGGAGATGAGTC
AGAATTATCGATTCGACAGCTGGCTCGTATCGAAAAAGGTCAATCTATTCCTAGTTTAGCCAAAGTCTTATTTATTGCAA
AAAAATTAGAATTACCTGTCGTTGAACTTATCAATCCAGAGTGCTTGGTTTTACCAAAACGTTATAAGGAGCTTAAATAT
CTGATTCTTAGGCGGCCAACCTACATGAATGGTCAAAATTTGGTGGATCGCGAAGCTCAATTTGATGAAATATTTGAAGA
TTATTATGCGACATTGCCTGAAGAAGAGCAGCTAATCATTGATTTATTACAGTCTCGGTTTGATGTCTACCAAAGTGGTG
ACACTAATTATGGTAAAGAATTACTCCGTGAGTATATTAGCCAAATTCGTAAGAAAAAGAGTTATGCTTTAAATGATATT
TTTTTGATAGATCTTTACCTGACTTGTGGTATGGTTTCAAACTTTAAGGAAGAATTGTTCGATAAGGGAAATTTTGATTG
TTTCACCAATAAATTAGTTCTTTTGGAAGATAAGTTAGAATTAAAAGATCTCTTTTTACTCAATAATGTTCTTCTCACCT
CCATCGCTGTGGGAATTAGTATTAAAGAATATCAGAAAACAAGAATACTTCTGAATGTCTGTCGGCGGATTATGACAATT
ACCCAAGACTTTCAGCGTATGCCTATTTATTACATGTACGAATGGAAATACACTTTATTTTATATGAAAGACTCTCAAAA
GGCTTATTATTATTACCGTCAATCTCTAATATTTGCACGAACACTAACCGATAATTACCTTGTTAATCGTTTAAAAACAA
GTTGGGAATTAGATAATCAATCGTAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(72-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0GXT6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

50

99.003

0.495
  comR Streptococcus pyogenes MGAS8232

45.183

100

0.452
  comR Streptococcus mutans UA159

44.186

100

0.442
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

43.945

96.013

0.422
  comR Streptococcus suis P1/7

37.748

100

0.379
  comR Streptococcus suis 05ZYH33

37.748

100

0.379

Multiple sequence alignment