Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL23_RS08520 Genome accession   NZ_LR594049
Coordinates   1775823..1776551 (-) Length   242 a.a.
NCBI ID   WP_045773605.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770823..1781551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS08500 (NCTC10231_01696) - 1771230..1772462 (-) 1233 WP_061603321.1 cysteine desulfurase -
  FGL23_RS08505 (NCTC10231_01697) sufD 1772502..1773764 (-) 1263 WP_061603322.1 Fe-S cluster assembly protein SufD -
  FGL23_RS08510 (NCTC10231_01698) sufC 1773806..1774576 (-) 771 WP_061603323.1 Fe-S cluster assembly ATPase SufC -
  FGL23_RS08515 (NCTC10231_01699) - 1774663..1775829 (-) 1167 WP_061603324.1 glycosyltransferase family 4 protein -
  FGL23_RS08520 (NCTC10231_01700) mecA 1775823..1776551 (-) 729 WP_045773605.1 adaptor protein MecA Regulator
  FGL23_RS08525 (NCTC10231_01701) - 1776673..1777521 (-) 849 WP_061603325.1 undecaprenyl-diphosphate phosphatase -
  FGL23_RS08530 (NCTC10231_01702) - 1777610..1779529 (-) 1920 WP_061603452.1 DUF2207 domain-containing protein -
  FGL23_RS08535 (NCTC10231_01703) - 1779826..1781391 (+) 1566 WP_061603326.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28289.92 Da        Isoelectric Point: 4.1489

>NTDB_id=1127987 FGL23_RS08520 WP_045773605.1 1775823..1776551(-) (mecA) [Streptococcus gordonii strain NCTC10231]
MEVKQISESTIKITIKLEDLEEHGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKV
DKNLNFEDLADLPDMDELSQMTPDEFLKTLEKNIFEKSRDDIDAVQMLEKAEEEDTSEPEEGQEQDRYIYYILRFSDLKN
LIAFTKTVNYPVDTSELYKMDQHYYLTILVDIEGRPSRYPAWLLAAMREHAEDTDTTRALLQEHGHLLIVTDAVQHLQKV
NC

Nucleotide


Download         Length: 729 bp        

>NTDB_id=1127987 FGL23_RS08520 WP_045773605.1 1775823..1776551(-) (mecA) [Streptococcus gordonii strain NCTC10231]
ATGGAAGTGAAGCAAATTAGTGAATCAACAATCAAGATCACCATCAAATTAGAAGATCTAGAAGAGCATGGTATGGAAAT
GGCTGATTTTCTGGTTCCTCAAGAAAAGACGGAGGAATTTTTCTATACCATTTTGGACGAACTAGAAATGCCAGAAAGCT
TTTTAGATAGTGGAATGCTGAGTTTTCGGGTGACTCCAAAACCAGACAAATTAGACGTTTTTGTCACAAAATCTAAAGTA
GATAAAAATTTAAATTTTGAAGATTTGGCTGACTTGCCTGATATGGACGAACTTTCTCAAATGACTCCGGATGAATTTCT
AAAGACGCTTGAAAAAAACATCTTTGAAAAAAGCCGTGATGATATAGATGCTGTTCAAATGCTGGAAAAAGCAGAAGAGG
AAGATACATCTGAACCAGAGGAAGGGCAAGAACAAGATCGCTATATTTATTATATCTTGCGTTTTTCTGACTTGAAAAAC
CTGATTGCATTCACCAAAACAGTCAACTATCCGGTGGATACATCAGAGTTATACAAGATGGATCAGCATTACTATTTGAC
TATTCTAGTAGATATTGAAGGTCGTCCGAGTCGTTATCCTGCTTGGCTTCTGGCAGCAATGCGTGAACATGCTGAGGATA
CAGATACGACGAGAGCCCTTCTTCAAGAGCACGGTCACTTGTTGATTGTAACAGATGCTGTGCAACATCTTCAAAAGGTA
AACTGCTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.714

100

0.665
  mecA Streptococcus pneumoniae D39

65.714

100

0.665
  mecA Streptococcus pneumoniae R6

65.714

100

0.665
  mecA Streptococcus pneumoniae TIGR4

65.714

100

0.665
  mecA Streptococcus mutans UA159

51.852

100

0.521
  mecA Streptococcus thermophilus LMD-9

48.193

100

0.496
  mecA Streptococcus thermophilus LMG 18311

47.791

100

0.492

Multiple sequence alignment