Detailed information NTG1127829

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FGL21_RS00420
• Genome accession: NZ_LR594047
• Coordinates: 62620..63531 (+)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0AAE9U6L1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 57620..68531

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL21_RS00395 (NCTC11554_00080)	purE	58120..58608 (+)	489	WP_003055559.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
FGL21_RS00400 (NCTC11554_00081)	purK	58595..59668 (+)	1074	WP_003055561.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
FGL21_RS00405 (NCTC11554_00082)	-	59678..60934 (+)	1257	WP_003055555.1	DUF4041 domain-containing protein	-
FGL21_RS00410	-	60927..61136 (+)	210	WP_014611912.1	hypothetical protein	-
FGL21_RS00415 (NCTC11554_00083)	purB	61185..62477 (+)	1293	WP_003056595.1	adenylosuccinate lyase	-
FGL21_RS00420 (NCTC11554_00084)	comR	62620..63531 (+)	912	WP_003060893.1	XRE family transcriptional regulator	Regulator
FGL21_RS11340 (NCTC11554_00085)	comS	63618..63716 (+)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
FGL21_RS00425 (NCTC11554_00086)	ruvB	63750..64748 (+)	999	WP_138127909.1	Holliday junction branch migration DNA helicase RuvB	-
FGL21_RS00430 (NCTC11554_00087)	-	64883..65314 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
FGL21_RS00435 (NCTC11554_00088)	-	65343..65744 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
FGL21_RS00440 (NCTC11554_00089)	-	65741..67516 (+)	1776	WP_138127911.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=1127829 FGL21_RS00420 WP_003060893.1 62620..63531(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=1127829 FGL21_RS00420 WP_003060893.1 62620..63531(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363