Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL18_RS01920 Genome accession   NZ_LR594046
Coordinates   358562..359323 (+) Length   253 a.a.
NCBI ID   WP_138124792.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 353562..364323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS01905 (NCTC6403_00390) - 353820..355388 (-) 1569 WP_138124788.1 ABC transporter substrate-binding protein/permease -
  FGL18_RS01910 (NCTC6403_00391) - 355587..357512 (+) 1926 WP_138124790.1 DUF2207 domain-containing protein -
  FGL18_RS01915 (NCTC6403_00392) - 357579..358418 (+) 840 WP_030127654.1 undecaprenyl-diphosphate phosphatase -
  FGL18_RS01920 (NCTC6403_00393) mecA 358562..359323 (+) 762 WP_138124792.1 adaptor protein MecA Regulator
  FGL18_RS01925 (NCTC6403_00394) - 359330..360499 (+) 1170 WP_138124794.1 MraY family glycosyltransferase -
  FGL18_RS01930 (NCTC6403_00395) sufC 360612..361382 (+) 771 WP_003061584.1 Fe-S cluster assembly ATPase SufC -
  FGL18_RS01935 (NCTC6403_00396) sufD 361479..362741 (+) 1263 WP_138124796.1 Fe-S cluster assembly protein SufD -
  FGL18_RS01940 (NCTC6403_00397) - 362772..363998 (+) 1227 WP_138124798.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29055.68 Da        Isoelectric Point: 4.0755

>NTDB_id=1127781 FGL18_RS01920 WP_138124792.1 358562..359323(+) (mecA) [Streptococcus dysgalactiae strain NCTC6403]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPEPLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1127781 FGL18_RS01920 WP_138124792.1 358562..359323(+) (mecA) [Streptococcus dysgalactiae strain NCTC6403]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCCGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCTAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTCTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.8

98.814

0.64
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482

Multiple sequence alignment