Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   FGL05_RS06725 Genome accession   NZ_LR594044
Coordinates   1369281..1371194 (-) Length   637 a.a.
NCBI ID   WP_058813683.1    Uniprot ID   A0AB38G4S0
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1364281..1376194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS06700 (NCTC8796_01424) - 1364955..1365311 (-) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  FGL05_RS09615 (NCTC8796_01425) - 1365311..1366711 (-) 1401 WP_081048448.1 Cof-type HAD-IIB family hydrolase -
  FGL05_RS06710 (NCTC8796_01426) - 1366835..1367479 (-) 645 WP_020916314.1 response regulator transcription factor -
  FGL05_RS06715 (NCTC8796_01427) - 1367463..1368488 (-) 1026 WP_020916313.1 sensor histidine kinase -
  FGL05_RS06720 (NCTC8796_01428) liaF 1368485..1369180 (-) 696 WP_058813684.1 cell wall-active antibiotics response protein LiaF -
  FGL05_RS06725 (NCTC8796_01429) stkP/pknB 1369281..1371194 (-) 1914 WP_058813683.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FGL05_RS06730 (NCTC8796_01430) - 1371194..1371931 (-) 738 WP_043894973.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FGL05_RS06735 (NCTC8796_01431) rsmB 1371969..1373291 (-) 1323 WP_111712651.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FGL05_RS06740 (NCTC8796_01432) fmt 1373281..1374216 (-) 936 WP_020916308.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69060.91 Da        Isoelectric Point: 6.5221

>NTDB_id=1127686 FGL05_RS06725 WP_058813683.1 1369281..1371194(-) (stkP/pknB) [Streptococcus lutetiensis strain NCTC8796]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLTKQKAAKVN
REAADNKIAKAKTKKKKSHRMFGTLVKIFFAVVVVAIAIFTYLTLSTPASVNVPDVAGTSLQAAKTSLTSAGLKVGRTKG
IYSDTVPSGQVIETNPKAGTSKKEGAKVDIYVSKGTSGFKMKDYTGQNYQEVIKELKDKHGISSDKIDVEWITGTNYDGG
TIISQTPEKGTKVASEDKITFKVAAIVMPNLIGYTYQDAIAELTALGLSSSHIIVFQADATSSTGYSQVKTPSASAVVVA
QDPYFGASIEGEVNLYFSARSEAQSSEVAPSQSVSESYETSETSESSSLSSSSSSSSSSSSSSSTEESSQTDSSSVE

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=1127686 FGL05_RS06725 WP_058813683.1 1369281..1371194(-) (stkP/pknB) [Streptococcus lutetiensis strain NCTC8796]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAGTCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTAATTCTTGATAATGAAGAAGTGGCTATCAAAGTCCTTCGAACTAATTATCAAACAGATCAAATTG
CCGTTGCTCGTTTCCAACGTGAAGCACGTGCCATGGCAGAGCTAAACCATCCAAATATCGTTTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAAAAATATATTCAAGACCACGCCCC
TCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTGTCTGCGATGACTTTGGCTCATCAACAAGGAATTGTTC
ACCGTGATTTGAAACCACAAAATATCTTGTTAACCAAAGACGGAACGGTTAAAGTTACCGACTTTGGTATCGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAAACAAACTCAATGCTTGGTAGTGTACACTATTTATCACCTGAACAAGCGCGTGGTTC
AAAAGCCACTGTTCAAAGTGATATCTACGCTATGGGGATTATGTTGTTTGAAATGTTGACTGGTCACATTCCATATGATG
GTGATTCAGCTGTTACGATTGCTCTTCAACATTTCCAAAAACCACTTCCATCAATCATTGATGAAAATAAAAATGTTCCA
CAAGCTTTGGAAAATGTTGTCATTAAAGCAACTGCAAAACGTTTGAGTGATCGCTACGCCTCAACTTTTGAAATGAGTCG
TGATTTAATGACTGCTCTCTCATATAACCGTAGCCGCGAACGCAAACTTGTCTTTGAAGATACAGAAAATACGAAGACAC
TTCCAAAAGTAACAACTTCAACACCTGTTCCCTCAACAACAGAACAATTGTTGACAAAACAAAAAGCAGCTAAAGTTAAT
CGTGAAGCTGCGGATAATAAAATTGCAAAAGCGAAAACGAAGAAGAAAAAATCACATCGTATGTTTGGTACTTTAGTGAA
AATTTTCTTTGCGGTCGTAGTAGTTGCAATTGCTATCTTTACTTACTTGACGCTAAGCACACCAGCTTCAGTCAACGTTC
CAGATGTAGCTGGAACAAGTTTACAAGCTGCTAAGACAAGTCTTACATCAGCAGGACTTAAAGTTGGAAGGACCAAGGGA
ATTTATAGTGATACTGTTCCAAGTGGTCAGGTTATTGAGACTAATCCGAAAGCTGGCACATCTAAGAAAGAAGGTGCCAA
AGTTGACATTTATGTGTCAAAAGGAACATCAGGCTTTAAGATGAAAGATTATACTGGTCAAAACTATCAAGAAGTTATCA
AAGAACTCAAAGATAAACACGGTATTTCAAGTGATAAGATTGATGTTGAATGGATAACAGGCACTAACTATGATGGTGGT
ACTATCATTAGTCAAACACCTGAAAAAGGTACAAAAGTTGCTAGTGAAGATAAGATTACTTTCAAGGTTGCAGCAATCGT
TATGCCAAACCTTATTGGTTATACTTATCAAGATGCAATTGCTGAATTGACTGCACTTGGCTTATCAAGTTCGCATATTA
TAGTATTCCAAGCAGATGCTACTTCATCAACTGGATATTCTCAAGTTAAAACACCATCTGCCTCTGCAGTTGTTGTGGCA
CAAGATCCTTACTTTGGCGCATCTATTGAAGGAGAGGTTAACCTTTACTTCTCAGCTAGAAGTGAAGCTCAGTCTTCAGA
AGTTGCACCATCTCAATCTGTTTCTGAGTCATATGAGACAAGTGAAACTAGTGAGTCAAGTTCTTTAAGTAGCAGCAGTA
GCAGCAGTAGCAGCAGTAGTAGCAGTAGCAGCACTGAAGAAAGTTCACAAACCGACTCATCATCAGTTGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-578)

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-503)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

59.685

99.686

0.595
  pknB Streptococcus mutans UA159

65.559

89.796

0.589
  stkP Streptococcus pneumoniae TIGR4

58.757

83.359

0.49
  stkP Streptococcus pneumoniae D39

58.569

83.359

0.488
  stkP Streptococcus pneumoniae R6

58.569

83.359

0.488
  stkP Streptococcus pneumoniae Rx1

58.38

83.359

0.487

Multiple sequence alignment