Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FGL05_RS04330 Genome accession   NZ_LR594044
Coordinates   878806..879480 (+) Length   224 a.a.
NCBI ID   WP_020916820.1    Uniprot ID   A0AB33ALR7
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 873806..884480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS04315 (NCTC8796_00923) pstB 874422..875180 (+) 759 WP_020916823.1 phosphate ABC transporter ATP-binding protein PstB -
  FGL05_RS04320 (NCTC8796_00924) phoU 875211..875864 (+) 654 WP_020916822.1 phosphate signaling complex protein PhoU -
  FGL05_RS04325 (NCTC8796_00925) - 876095..878638 (+) 2544 WP_111712817.1 M1 family metallopeptidase -
  FGL05_RS04330 (NCTC8796_00926) ciaR 878806..879480 (+) 675 WP_020916820.1 response regulator transcription factor Regulator
  FGL05_RS04335 (NCTC8796_00927) ciaH 879470..880798 (+) 1329 WP_020916819.1 HAMP domain-containing sensor histidine kinase Regulator
  FGL05_RS04340 - 880867..882215 (+) 1349 WP_111712816.1 IS3 family transposase -
  FGL05_RS04345 (NCTC8796_00930) rpsT 882317..882568 (-) 252 WP_004231769.1 30S ribosomal protein S20 -
  FGL05_RS04350 (NCTC8796_00931) coaA 882644..883564 (-) 921 WP_020916817.1 type I pantothenate kinase -
  FGL05_RS04355 (NCTC8796_00932) - 883696..884289 (+) 594 WP_061407804.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25402.03 Da        Isoelectric Point: 4.3421

>NTDB_id=1127674 FGL05_RS04330 WP_020916820.1 878806..879480(+) (ciaR) [Streptococcus lutetiensis strain NCTC8796]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKGGFQVLKELREQGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNDNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1127674 FGL05_RS04330 WP_020916820.1 878806..879480(+) (ciaR) [Streptococcus lutetiensis strain NCTC8796]
ATGATTAAGATTTTATTAGTAGAAGATGATTTGAGTTTATCGAATTCAATCTTTGATTTTTTAGACGATTTTGCGGATGT
TATGCAAGTCTTTGATGGTGAAGAAGGACTTTATGAGGCAGAAAGTGGTGTTTATGACCTTATTTTGCTTGATCTGATGT
TGCCAGAAAAAGGTGGTTTCCAAGTTCTGAAAGAATTACGTGAACAAGGTATTACGACACCTGTCTTAATTATGACTGCA
AAAGAAAGCCTTGATGATAAAGGACATGGCTTTGAACTTGGTGCAGATGACTATTTGACAAAACCATTTTATCTCGAAGA
ATTAAAGATGCGCATTCAAGCGCTTTTGAAACGCTCTGGAAAATTCAACGATAATACTCTTTCTTACCACGAATTAACAG
CCGATACATCAACTAACACAACAACTGTTAACGGTGAAAAGGTTGAGTTACTAGGTAAAGAATTTGATTTACTGGTTTAT
TTCTTGCAAAACCAAAATGTTATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGATTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGCAAAAAATTAAAAGGAACAAGTTTTGCTAAAAATCTACAAACACTTC
GTAGTGTAGGATATATTCTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.946

100

0.879
  ciaR Streptococcus pneumoniae D39

87.946

100

0.879
  ciaR Streptococcus pneumoniae R6

87.946

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.885

100

0.384
  vicR Streptococcus mutans UA159

34.764

100

0.362

Multiple sequence alignment