Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   FGL16_RS02350 Genome accession   NZ_LR594043
Coordinates   422719..424713 (+) Length   664 a.a.
NCBI ID   WP_014735508.1    Uniprot ID   -
Organism   Streptococcus suis strain NCTC10237     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 417719..429713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL16_RS02335 (NCTC10237_00440) fmt 419706..420644 (+) 939 WP_014735505.1 methionyl-tRNA formyltransferase -
  FGL16_RS02340 (NCTC10237_00441) rsmB 420631..421944 (+) 1314 WP_014735506.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FGL16_RS02345 (NCTC10237_00442) - 421982..422719 (+) 738 WP_014735507.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FGL16_RS02350 (NCTC10237_00443) stkP 422719..424713 (+) 1995 WP_014735508.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FGL16_RS02355 (NCTC10237_00444) liaF 425002..425697 (+) 696 WP_012774984.1 cell wall-active antibiotics response protein LiaF -
  FGL16_RS02360 (NCTC10237_00445) - 425694..426710 (+) 1017 WP_014735509.1 sensor histidine kinase -
  FGL16_RS02365 (NCTC10237_00446) - 426682..427323 (+) 642 WP_014735510.1 response regulator transcription factor -
  FGL16_RS02370 (NCTC10237_00447) - 427373..428773 (+) 1401 WP_014735511.1 Cof-type HAD-IIB family hydrolase -
  FGL16_RS02375 (NCTC10237_00448) - 428775..429146 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71573.21 Da        Isoelectric Point: 6.7857

>NTDB_id=1127620 FGL16_RS02350 WP_014735508.1 422719..424713(+) (stkP) [Streptococcus suis strain NCTC10237]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KSPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVALQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVINTDPVANTELAKG
SIINLVISKGKELIMPDLTSRNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=1127620 FGL16_RS02350 WP_014735508.1 422719..424713(+) (stkP) [Streptococcus suis strain NCTC10237]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGGGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTTGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGGATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGACCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCTCAAGCCAATGTTGAAACGAAAGTACCGCATACAAATAGTTCCGCCCAAGTTTCTGCGACAGAT
AAGAGCCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCACGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCTACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAACACAGATCCCGTTGCTAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTCGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAACAGGAAGTTCCACAAGTACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(441-501)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.481

100

0.526
  stkP Streptococcus pneumoniae D39

52.331

100

0.524
  stkP Streptococcus pneumoniae R6

52.331

100

0.524
  stkP Streptococcus pneumoniae Rx1

52.18

100

0.523
  stkP/pknB Streptococcus salivarius strain HSISS4

52.316

87.801

0.459
  pknB Streptococcus mutans UA159

54.393

80.572

0.438

Multiple sequence alignment