Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL06_RS01650 Genome accession   NZ_LR594042
Coordinates   308866..309627 (+) Length   253 a.a.
NCBI ID   WP_027968236.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 303866..314627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS01635 (NCTC8133_00325) - 304272..305843 (-) 1572 WP_021141661.1 ABC transporter permease subunit -
  FGL06_RS01640 (NCTC8133_00326) - 305980..307872 (+) 1893 WP_126437594.1 DUF2207 domain-containing protein -
  FGL06_RS01645 (NCTC8133_00327) - 307924..308763 (+) 840 WP_003067592.1 undecaprenyl-diphosphate phosphatase -
  FGL06_RS01650 (NCTC8133_00328) mecA 308866..309627 (+) 762 WP_027968236.1 adaptor protein MecA Regulator
  FGL06_RS01655 (NCTC8133_00329) - 309629..310792 (+) 1164 WP_024344760.1 glycosyltransferase family 4 protein -
  FGL06_RS01660 (NCTC8133_00330) sufC 310914..311684 (+) 771 WP_021141665.1 Fe-S cluster assembly ATPase SufC -
  FGL06_RS01665 (NCTC8133_00331) sufD 311762..313024 (+) 1263 WP_126437595.1 Fe-S cluster assembly protein SufD -
  FGL06_RS01670 (NCTC8133_00332) - 313026..314258 (+) 1233 WP_126437596.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29032.82 Da        Isoelectric Point: 4.0128

>NTDB_id=1127555 FGL06_RS01650 WP_027968236.1 308866..309627(+) (mecA) [Streptococcus equinus strain NCTC8133]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMMAKGDTEAHEKLGKIEEMMEGAVEEVLTENAKQADTEPEEDVNPSDYVH
YVLDFPSLEATVAFSKAIDFPVEASELYKMDGAYYMTILLDLQNQPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVAKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1127555 FGL06_RS01650 WP_027968236.1 308866..309627(+) (mecA) [Streptococcus equinus strain NCTC8133]
ATGGAAATGAAACAGATCAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGAGGAATGGAGTT
AAAAGACTTTTTGATTCCGCAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAGTTAGATTTACCAGATAATT
TCAAAGATAGCGGCATGCTTAGCTTTCGTGTGACACCACGTAAAGACCGTCTTGATGTATTTGTCACAAAATCAGAAATT
AACAAAGATATCAATTTTGAAGATTTAGCTGCATTTGACGATGTGTCTAACATGTCACCAGAAGAATTCTTTAAAACGTT
AGAACAAACAATGATGGCTAAAGGTGACACTGAAGCTCATGAAAAATTAGGTAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAAGAAGTCTTGACAGAGAACGCTAAGCAAGCAGATACAGAACCTGAAGAAGATGTGAACCCATCTGATTATGTTCAT
TACGTCTTAGATTTTCCAAGTTTAGAAGCGACAGTTGCTTTTTCTAAAGCGATTGATTTTCCTGTGGAAGCTTCTGAGCT
TTACAAGATGGATGGCGCTTATTACATGACAATTTTGCTTGATTTGCAGAACCAACCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTACTTGCAAGAGCACGCAGTTGAATTATTGACG
GATGATGCCGTTGCAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.4

98.814

0.656
  mecA Streptococcus thermophilus LMD-9

60.643

98.419

0.597
  mecA Streptococcus thermophilus LMG 18311

59.839

98.419

0.589
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment