Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL12_RS08785 Genome accession   NZ_LR594041
Coordinates   1823725..1824453 (-) Length   242 a.a.
NCBI ID   WP_012130768.1    Uniprot ID   A8AYY6
Organism   Streptococcus gordonii strain NCTC9124     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1818725..1829453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS08765 (NCTC9124_01766) - 1819132..1820364 (-) 1233 WP_012130765.1 cysteine desulfurase -
  FGL12_RS08770 (NCTC9124_01767) sufD 1820404..1821666 (-) 1263 WP_012130766.1 Fe-S cluster assembly protein SufD -
  FGL12_RS08775 (NCTC9124_01768) sufC 1821708..1822478 (-) 771 WP_008809634.1 Fe-S cluster assembly ATPase SufC -
  FGL12_RS08780 (NCTC9124_01769) - 1822565..1823731 (-) 1167 WP_008809635.1 MraY family glycosyltransferase -
  FGL12_RS08785 (NCTC9124_01770) mecA 1823725..1824453 (-) 729 WP_012130768.1 adaptor protein MecA Regulator
  FGL12_RS08790 (NCTC9124_01771) - 1824575..1825423 (-) 849 WP_012130769.1 undecaprenyl-diphosphate phosphatase -
  FGL12_RS08795 (NCTC9124_01772) - 1825512..1827503 (-) 1992 WP_263285760.1 DUF2207 domain-containing protein -
  FGL12_RS08800 (NCTC9124_01773) - 1827716..1829281 (+) 1566 WP_012130771.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28309.96 Da        Isoelectric Point: 4.1285

>NTDB_id=1127513 FGL12_RS08785 WP_012130768.1 1823725..1824453(-) (mecA) [Streptococcus gordonii strain NCTC9124]
MEVKQISESTIKITIKLEDLEEHGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKV
DKNLNFEDLADLPDMDELSQMTPDEFLKTLEKNIFEKSRDDIDAVQMLEKAEEEDTSEPEEGQEQDRYIYYILRFSDLKN
LIAFTKTVDYPVDTSELYKMDQRYYLTILVDIEGRPSRYPAWLLAAMREHAEDTDTTRALLQEHGHLLIVTDAVQHLQKV
NC

Nucleotide


Download         Length: 729 bp        

>NTDB_id=1127513 FGL12_RS08785 WP_012130768.1 1823725..1824453(-) (mecA) [Streptococcus gordonii strain NCTC9124]
ATGGAAGTGAAGCAAATTAGTGAATCAACAATTAAGATCACCATTAAATTAGAAGATTTAGAAGAGCACGGCATGGAGAT
GGCAGATTTTCTGGTTCCTCAGGAAAAGACGGAGGAATTTTTCTATACCATTTTGGACGAACTAGAAATGCCAGAAAGCT
TTTTAGATAGTGGAATGCTGAGTTTTCGGGTGACTCCAAAACCAGACAAATTAGACGTTTTTGTCACAAAATCTAAAGTA
GACAAAAATTTAAATTTTGAAGATTTGGCTGACTTGCCTGATATGGACGAACTTTCTCAAATGACTCCGGATGAATTTCT
AAAGACGCTTGAAAAAAACATCTTTGAAAAAAGCCGTGATGATATAGATGCAGTTCAAATGCTGGAAAAAGCGGAAGAGG
AAGATACATCTGAACCAGAGGAAGGGCAAGAACAAGATCGCTATATTTATTATATCTTGCGTTTTTCTGACTTGAAAAAT
CTGATTGCATTCACCAAAACAGTCGACTATCCGGTGGATACATCAGAGTTATACAAGATGGATCAGCGTTACTATTTGAC
TATTTTAGTAGATATTGAAGGTCGTCCGAGTCGTTATCCAGCTTGGCTTCTGGCAGCAATGCGTGAACATGCTGAGGATA
CAGATACGACGAGAGCCCTTCTTCAAGAGCACGGTCACTTGTTGATTGTAACAGATGCTGTGCAACATCTTCAAAAGGTA
AACTGCTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AYY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.122

100

0.669
  mecA Streptococcus pneumoniae D39

66.122

100

0.669
  mecA Streptococcus pneumoniae R6

66.122

100

0.669
  mecA Streptococcus pneumoniae TIGR4

66.122

100

0.669
  mecA Streptococcus mutans UA159

52.263

100

0.525
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.488

Multiple sequence alignment