Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   FGL12_RS03860 Genome accession   NZ_LR594041
Coordinates   802766..803467 (+) Length   233 a.a.
NCBI ID   WP_138101166.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC9124     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 797766..808467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS03835 (NCTC9124_00769) - 798109..799422 (+) 1314 WP_012000237.1 glycosyltransferase family 4 protein -
  FGL12_RS03840 (NCTC9124_00770) - 799458..799820 (+) 363 WP_012000238.1 hypothetical protein -
  FGL12_RS10995 (NCTC9124_00772) - 800154..800525 (+) 372 WP_012000239.1 hypothetical protein -
  FGL12_RS03855 (NCTC9124_00773) thrS 800617..802560 (+) 1944 WP_012000240.1 threonine--tRNA ligase -
  FGL12_RS03860 (NCTC9124_00774) micA 802766..803467 (+) 702 WP_138101166.1 response regulator YycF Regulator
  FGL12_RS03865 (NCTC9124_00775) micB 803460..804821 (+) 1362 WP_138101167.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL12_RS03870 (NCTC9124_00776) vicX 804814..805617 (+) 804 WP_008809002.1 MBL fold metallo-hydrolase Regulator
  FGL12_RS03875 (NCTC9124_00777) - 805652..806008 (+) 357 WP_008809001.1 YbaN family protein -
  FGL12_RS03880 (NCTC9124_00778) rnc 806251..806949 (+) 699 WP_012000242.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26785.50 Da        Isoelectric Point: 4.6297

>NTDB_id=1127489 FGL12_RS03860 WP_138101166.1 802766..803467(+) (micA) [Streptococcus gordonii strain NCTC9124]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLVLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQENEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1127489 FGL12_RS03860 WP_138101166.1 802766..803467(+) (micA) [Streptococcus gordonii strain NCTC9124]
ATGAAGAAAATATTAGTTGTAGATGATGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTCTTGAGATGTTTGAAGCTGAAAATCCTGATATTTTGATTTTGGATTTGG
TGTTGCCAGAGTTGGACGGGCTAGAAGTAGCACGCACCATTCGGAAGACCAGTAATGTTCCAATTATTGTCCTATCGGCT
AAAGATAGTGAGTTTGATAAAGTTATCGGCCTTGAGATCGGAGCAGACGACTATGTGACTAAGCCTTTCTCTAACCGTGA
GCTCCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCAGAATTTGCTGTAGATACCCAAGAAAATGAAAAGGGCTCAAATG
AGTTGACAGTGGGTGAATTGCAAATTTTACCCGATGCTTTTGTTGCCAAAAAACATGGTGAAGAGCTAGAATTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCTAGTCATGTTGGTCAAGTAATGACACGCGAACACCTGTTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGATGTACGCACTGTTGATGTGACGATTCGCCGTCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGTGTTGGCTACTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.691

100

0.837
  vicR Streptococcus mutans UA159

79.574

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.589

99.142

0.442
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429
  scnR Streptococcus mutans UA159

37.069

99.571

0.369

Multiple sequence alignment