Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   FGL12_RS03005 Genome accession   NZ_LR594041
Coordinates   643767..644432 (+) Length   221 a.a.
NCBI ID   WP_012000103.1    Uniprot ID   A8AVW5
Organism   Streptococcus gordonii strain NCTC9124     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 638767..649432
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS02980 (NCTC9124_00596) - 638931..640334 (+) 1404 WP_012000098.1 Cof-type HAD-IIB family hydrolase -
  FGL12_RS02985 (NCTC9124_00597) - 640331..640717 (+) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -
  FGL12_RS02990 (NCTC9124_00598) cysK 640754..641683 (-) 930 WP_012000100.1 cysteine synthase A -
  FGL12_RS02995 (NCTC9124_00599) - 641781..642413 (-) 633 WP_041789573.1 YigZ family protein -
  FGL12_RS03000 (NCTC9124_00600) comFA/cflA 642469..643770 (+) 1302 WP_012000102.1 DEAD/DEAH box helicase Machinery gene
  FGL12_RS03005 (NCTC9124_00601) comFC/cflB 643767..644432 (+) 666 WP_012000103.1 ComF family protein Machinery gene
  FGL12_RS03010 (NCTC9124_00602) raiA 644520..645062 (+) 543 WP_012000104.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25895.01 Da        Isoelectric Point: 8.4502

>NTDB_id=1127482 FGL12_RS03005 WP_012000103.1 643767..644432(+) (comFC/cflB) [Streptococcus gordonii strain NCTC9124]
MKQCLICLAILEEQLNFMDLLLLKRKENDICQECLNSFEEIPEEHCPTCYKAGDKKLCKDCQYWQERGLEVAHKSLYTYN
KAMKDYFSRYKFQGDYLLRNVFALSLRKELKNFQSYTILSIPLSESKMRKRGFNQVSGLLEAAQIPYQEILKKKESQTQS
SKDRKERLENTGNFYMIENTKIPKKILLVDDIYTTGATLQDAKLTLFENGAKEIMTFSLAR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1127482 FGL12_RS03005 WP_012000103.1 643767..644432(+) (comFC/cflB) [Streptococcus gordonii strain NCTC9124]
ATGAAACAATGTCTAATCTGCTTAGCTATATTAGAAGAGCAGTTGAATTTTATGGATTTATTACTATTAAAAAGAAAAGA
AAATGACATTTGTCAAGAATGCTTAAATTCCTTCGAAGAAATTCCAGAAGAACATTGTCCAACCTGTTATAAAGCTGGGG
ACAAAAAATTGTGCAAAGATTGTCAGTACTGGCAGGAAAGAGGATTAGAAGTAGCGCATAAAAGTTTGTACACTTATAAT
AAAGCAATGAAAGACTATTTTAGTCGCTACAAATTTCAAGGAGATTATCTTTTAAGAAATGTATTTGCCTTAAGCCTAAG
AAAAGAGTTAAAAAATTTTCAAAGCTACACAATTTTAAGCATTCCTTTAAGTGAGAGTAAGATGAGAAAAAGAGGATTCA
ATCAAGTGTCAGGATTACTTGAAGCTGCACAAATACCTTATCAAGAGATATTAAAGAAAAAAGAAAGTCAAACACAGTCT
AGTAAAGACAGAAAAGAAAGATTAGAAAACACAGGGAATTTTTACATGATTGAAAATACGAAAATCCCGAAAAAAATTTT
ACTTGTAGATGACATCTATACAACAGGAGCAACCTTGCAAGATGCAAAATTGACATTATTTGAAAATGGAGCGAAAGAAA
TCATGACATTTTCATTAGCAAGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AVW5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

49.772

99.095

0.493
  comFC/cflB Streptococcus mitis NCTC 12261

49.315

99.095

0.489
  comFC/cflB Streptococcus pneumoniae Rx1

49.315

99.095

0.489
  comFC/cflB Streptococcus pneumoniae D39

49.315

99.095

0.489
  comFC/cflB Streptococcus pneumoniae R6

49.315

99.095

0.489
  comFC/cflB Streptococcus mitis SK321

48.858

99.095

0.484

Multiple sequence alignment