Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   FGK97_RS01885 Genome accession   NZ_LR594037
Coordinates   368043..369917 (+) Length   624 a.a.
NCBI ID   WP_106079183.1    Uniprot ID   -
Organism   Streptococcus anginosus strain NCTC11064     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 363043..374917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK97_RS01870 (NCTC11064_00376) fmt 365049..365984 (+) 936 WP_021001357.1 methionyl-tRNA formyltransferase -
  FGK97_RS01875 (NCTC11064_00377) rsmB 365974..367287 (+) 1314 WP_021001358.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FGK97_RS01880 (NCTC11064_00378) - 367306..368046 (+) 741 WP_003025814.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FGK97_RS01885 (NCTC11064_00379) stkP 368043..369917 (+) 1875 WP_106079183.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FGK97_RS01890 (NCTC11064_00380) liaF 370178..370876 (+) 699 WP_003025810.1 cell wall-active antibiotics response protein LiaF -
  FGK97_RS01895 (NCTC11064_00381) - 370873..371868 (+) 996 WP_138099347.1 sensor histidine kinase -
  FGK97_RS01900 (NCTC11064_00382) - 371870..372502 (+) 633 WP_003025807.1 response regulator transcription factor -
  FGK97_RS01905 (NCTC11064_00383) - 372542..373942 (+) 1401 WP_084740924.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGK97_RS01910 (NCTC11064_00384) - 373944..374318 (+) 375 WP_021001363.1 S1 RNA-binding domain-containing protein -
  FGK97_RS01915 (NCTC11064_00385) - 374444..374761 (-) 318 WP_041784094.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67655.77 Da        Isoelectric Point: 9.4135

>NTDB_id=1127403 FGK97_RS01885 WP_106079183.1 368043..369917(+) (stkP) [Streptococcus anginosus strain NCTC11064]
MIQVGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKPTPAPTKEAVS
SKPTPKPKAKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTP
AAGSTYDLTSKTRITLKVAKSISSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQAPEAGQS
LNLKSDRIILYVYEPKTEDSSTSESSSQSDSSSDKTSPSSSSSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=1127403 FGK97_RS01885 WP_106079183.1 368043..369917(+) (stkP) [Streptococcus anginosus strain NCTC11064]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAAAATCATCAAACAAATTGGTCGAGGTGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAATTACCAGACGGATCCAATTG
CTGTAGCACGTTTTCAAAGAGAAGCACGCGCCATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGTCAGCAGTATCTAGCAATGGAATATGTGGCTGGACTCGACTTAAAGCGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCACACACGCACGGGATTGTTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTCACTGACTTTGGAATTGCGGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGCTGGGATCTGTGCATTATCTATCACCAGAACAGGCACGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGACG
GAGATAGTGCTGTTACAATTGCTTTACAGCATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAATGTTCCA
CAAGCATTAGAAAATGTAGTCATCAAGGCAACGGCTAAAAAATTGACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
GGATTTATCAAGCTGTTTATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACGCTGCCGAAAGTGTCACAAAATACTTTGACTTCTGCGACGAAGCCAACACCTGCTCCCACAAAAGAAGCAGTCAGT
AGTAAACCTACGCCTAAGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGCTATAAAGTTTTGTTATCAGCAGTGGT
TTTAGTTATCGCAGCTCTGGTGGCTTTGGTCTATTTGAGTCCATCAAATGTAAAAATTCCAGATGTTACTGGAAAAACTA
TTGCCCAAGCACGTTCTGCAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGATTCAGTCATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCCATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCA
GCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATCACGTTAAAAGTAGCGAAGTCCATTTCAAGTGTCACGAT
GCCAAGCTATATCGGTTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAGCCCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTATCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTC
ACAATCTGATAGCAGCTCAGATAAAACTAGCCCATCCTCTAGCAGTTCGTCAACTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(364-427)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(433-500)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.705

94.391

0.62
  stkP Streptococcus pneumoniae D39

65.365

94.391

0.617
  stkP Streptococcus pneumoniae R6

65.365

94.391

0.617
  stkP Streptococcus pneumoniae Rx1

65.195

94.391

0.615
  pknB Streptococcus mutans UA159

59.145

93.75

0.554
  stkP/pknB Streptococcus salivarius strain HSISS4

55.686

95.833

0.534

Multiple sequence alignment