Detailed information NTG1127401

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: FGK97_RS01720
• Genome accession: NZ_LR594037
• Coordinates: 331946..332701 (+)
• Length: 251 a.a.
• NCBI ID: WP_003025888.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain NCTC11064
• Function: degradation of ComW (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	330467..331818	331946..332701	flank	128

Gene organization within MGE regions

Location: 330467..332701

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK97_RS01720 (NCTC11064_00346)	mecA	331946..332701 (+)	756	WP_003025888.1	adaptor protein MecA	Regulator

Sequence

Protein

• Length: 251 a.a.
• Molecular weight: 29095.86 Da
• Isoelectric Point: 4.1403

>NTDB_id=1127401 FGK97_RS01720 WP_003025888.1 331946..332701(+) (mecA) [Streptococcus anginosus strain NCTC11064]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAESDDNTSTSDMEEQDENSDELTQKYIYYI
LKFSSLKEAIVFSKTVDYAVNTSELYKMDDHYYLTILVDIEGHPKRYPAWLLASMREHAEDTDVTRAVLQEHGYLLLVNE
AVASLKKVKCL

Nucleotide

• Length: 756 bp

>NTDB_id=1127401 FGK97_RS01720 WP_003025888.1 331946..332701(+) (mecA) [Streptococcus anginosus strain NCTC11064]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACGATAAAATTAGAGGATTTAGAGGAACGTGGGATGGAAAT
GGCAGATTTTCTAGTCCCACAAGAAAAAACAGAAGAGTTTTTCTATGCGATTTTAGATGAGTTGGAAATGCCAGAAAGCT
TTTTAGATAGTGGCATGCTCAGTTTTCGTGTGACACCAAAGCCCGACCGATTGGATGTCTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAACTTCGATGATTTGGCGGATTTGCCAGATGTAGAAGAGTTGTCTCAAATGTCTCCTGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAATCAG
ACGATAACACAAGCACTTCTGATATGGAAGAACAAGATGAAAATAGTGACGAGCTAACGCAAAAATATATTTATTACATT
TTGAAATTTTCCAGCCTGAAAGAAGCAATTGTCTTTTCTAAGACAGTAGATTATGCTGTCAATACTTCGGAGTTGTACAA
AATGGACGATCACTATTATTTGACAATTCTGGTGGATATTGAGGGACACCCGAAGCGTTATCCAGCTTGGCTCCTTGCCT
CTATGCGTGAACATGCAGAAGACACAGATGTGACGAGAGCTGTTTTGCAAGAGCACGGTTATTTATTGCTTGTCAACGAG
GCGGTTGCCAGTCTTAAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-245)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus pneumoniae Rx1	65.323	98.805	0.645
mecA	Streptococcus pneumoniae D39	65.323	98.805	0.645
mecA	Streptococcus pneumoniae R6	65.323	98.805	0.645
mecA	Streptococcus pneumoniae TIGR4	65.323	98.805	0.645
mecA	Streptococcus mutans UA159	49.597	98.805	0.49
mecA	Streptococcus thermophilus LMD-9	46.275	100	0.47
mecA	Streptococcus thermophilus LMG 18311	45.882	100	0.466