Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   FGK96_RS08365 Genome accession   NZ_LR594036
Coordinates   1731468..1733399 (-) Length   643 a.a.
NCBI ID   WP_138083017.1    Uniprot ID   -
Organism   Streptococcus porcinus strain NCTC10710     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1726468..1738399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK96_RS08340 (NCTC10710_01729) - 1727237..1727590 (-) 354 WP_138083009.1 S1 RNA-binding domain-containing protein -
  FGK96_RS08345 (NCTC10710_01730) - 1727590..1728990 (-) 1401 WP_138083011.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGK96_RS08350 (NCTC10710_01731) - 1729024..1729665 (-) 642 WP_007892962.1 response regulator transcription factor -
  FGK96_RS08355 (NCTC10710_01732) - 1729658..1730662 (-) 1005 WP_138083013.1 sensor histidine kinase -
  FGK96_RS08360 (NCTC10710_01733) liaF 1730659..1731354 (-) 696 WP_138083015.1 cell wall-active antibiotics response protein LiaF -
  FGK96_RS08365 (NCTC10710_01734) pknB 1731468..1733399 (-) 1932 WP_138083017.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FGK96_RS08370 (NCTC10710_01735) - 1733396..1734136 (-) 741 WP_138083019.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FGK96_RS08375 (NCTC10710_01736) rsmB 1734175..1735497 (-) 1323 WP_138083021.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FGK96_RS08380 (NCTC10710_01737) fmt 1735490..1736422 (-) 933 WP_138083023.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 643 a.a.        Molecular weight: 69956.42 Da        Isoelectric Point: 9.1491

>NTDB_id=1127367 FGK96_RS08365 WP_138083017.1 1731468..1733399(-) (pknB) [Streptococcus porcinus strain NCTC10710]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHSNIVAIRDIG
EEDGQQFLVMEYVDGADLKKFIQDNAPLTNNQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLYEMLTGHIPYDGDSAVTIALQHFQKPLPSIVDENPSVP
QALENVVIKATAKKLSDRYATTFEMSRDLMTTLSYNRSREKKLIFDDGENTKPLPKVTPTLNTSPKSSPKVTTAPAKAAQ
ASEQLKKPKKEKKRGRFLGTLFKILFALFVVGVAIFTFLILTKPANVKVPNLSGRDLQAAKADLQTLGFKVGNIEQVPSD
EVAEGNVIETNPIAGTTKREGSKVDIIVSKGSSGFKVKDYVGDDYQKAMEDLMTTYGLKRKQIKIKRVIKDDYSKQDIVL
NQSPNKGYFNPNGKTKFTLTVATTEIIGMPQLIGMTYKNAKLLLEEKGIDLNRVKVYQMNPDGTTTPVEPSADTLIAYQN
PLLGGQVSLTDTGEISLYINSDSQHVPQSSSSSSSSTEASSESSTTSSGSSSTNSSSESSSGSSSTSTSTSTSTSTTSSN
TGQ

Nucleotide


Download         Length: 1932 bp        

>NTDB_id=1127367 FGK96_RS08365 WP_138083017.1 1731468..1733399(-) (pknB) [Streptococcus porcinus strain NCTC10710]
ATGATACAGATTGGCAAATTATTTGCTGGTCGATATCGCATATTAAAATCTATTGGCCGTGGAGGCATGGCAGATGTTTA
TTTAGCTAATGACTTAATCTTAGATAATGAAGATGTAGCAATAAAGGTATTGCGGACGAATTATCAAACGGATCAAGTTG
CTGTTGCACGTTTCCAAAGGGAAGCAAGAGCAATGGCTGAGCTGAATCATTCTAATATCGTAGCTATTAGAGATATAGGC
GAAGAAGACGGGCAGCAATTTTTAGTAATGGAATATGTTGATGGCGCTGACCTTAAGAAGTTCATTCAAGATAACGCACC
TTTGACTAACAATCAAGTGGTTCGGATTATGGAAGAAGTCTTGTCGGCAATGACTTTAGCCCATCAAAAAGGTATCGTTC
ATAGAGATTTAAAACCACAGAACATTCTTTTAACTAAAGAAGGTGTTGTCAAAGTCACAGACTTTGGTATTGCTGTTGCT
TTTGCGGAAACCAGCTTAACACAGACTAATTCCATGTTAGGGAGTGTTCATTATTTATCACCTGAACAGGCACGTGGCTC
AAAAGCAACCATTCAAAGTGATATCTATGCAATGGGAATCATGCTATATGAAATGTTAACTGGTCATATTCCCTATGATG
GAGATAGTGCGGTAACGATTGCTCTGCAACATTTTCAAAAACCGCTTCCTTCAATTGTAGATGAGAATCCTAGTGTGCCC
CAAGCTTTAGAAAATGTTGTTATTAAAGCAACTGCTAAAAAGTTAAGTGACCGTTATGCAACGACTTTTGAAATGAGCAG
AGATTTAATGACAACCTTGAGCTATAACCGTAGTCGTGAAAAGAAGTTGATTTTTGATGACGGTGAGAATACAAAACCTT
TGCCGAAAGTGACTCCTACGCTTAATACCAGTCCTAAATCAAGTCCTAAGGTAACTACCGCTCCCGCTAAAGCAGCGCAG
GCTTCAGAACAGCTTAAAAAGCCTAAAAAAGAGAAAAAGCGAGGACGTTTCTTAGGAACTCTTTTCAAAATTTTATTTGC
TCTATTTGTGGTTGGTGTAGCCATCTTTACCTTCTTAATTTTAACAAAACCTGCTAATGTTAAGGTTCCTAACTTAAGTG
GTAGAGATTTACAGGCTGCAAAAGCAGATTTACAAACGCTGGGTTTTAAAGTTGGGAATATTGAACAAGTACCAAGCGAT
GAAGTTGCAGAAGGAAATGTTATTGAAACGAATCCGATTGCAGGAACAACAAAACGTGAGGGTTCTAAGGTAGACATTAT
AGTCTCTAAAGGAAGTAGTGGCTTTAAAGTTAAGGATTATGTAGGTGATGATTATCAAAAGGCTATGGAAGACTTAATGA
CTACTTACGGTTTAAAACGTAAACAAATAAAGATTAAACGTGTTATCAAAGATGATTATAGTAAGCAAGACATTGTTTTA
AACCAATCACCAAATAAGGGATATTTTAACCCCAACGGAAAAACGAAGTTTACTTTAACAGTTGCAACTACAGAAATAAT
TGGGATGCCACAACTCATTGGAATGACTTATAAGAATGCTAAACTCTTACTGGAAGAGAAAGGGATTGATTTAAATCGTG
TTAAGGTTTATCAGATGAACCCTGATGGGACTACGACACCGGTTGAACCAAGCGCTGATACACTAATTGCTTATCAAAAT
CCCCTACTTGGTGGACAGGTTTCGCTGACAGATACAGGAGAAATCAGTCTTTATATTAATAGTGATAGCCAGCATGTTCC
ACAATCAAGTAGCTCAAGTTCATCAAGTACAGAGGCTAGCTCTGAATCTAGCACTACTAGTTCAGGTTCTTCCAGCACCA
ATTCATCCTCTGAGTCGAGTTCTGGATCCAGCTCAACCAGCACCTCAACTAGCACCAGTACATCTACAACTAGTTCGAAT
ACAGGTCAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-233)

PASTA domain (PASTA)

(509-580)

PASTA domain (PASTA)

(367-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

62.607

90.669

0.568
  stkP/pknB Streptococcus salivarius strain HSISS4

60.642

92.068

0.558
  stkP Streptococcus pneumoniae TIGR4

62

69.984

0.434
  stkP Streptococcus pneumoniae D39

61.556

69.984

0.431
  stkP Streptococcus pneumoniae R6

61.556

69.984

0.431
  stkP Streptococcus pneumoniae Rx1

61.333

69.984

0.429

Multiple sequence alignment