Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGK96_RS08080 Genome accession   NZ_LR594036
Coordinates   1676821..1677576 (-) Length   251 a.a.
NCBI ID   WP_138082942.1    Uniprot ID   A0A4U9ZJX0
Organism   Streptococcus porcinus strain NCTC10710     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1677731..1679076 1676821..1677576 flank 155


Gene organization within MGE regions


Location: 1676821..1679076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK96_RS08080 (NCTC10710_01675) mecA 1676821..1677576 (-) 756 WP_138082942.1 adaptor protein MecA Regulator
  FGK96_RS08085 - 1677731..1679076 (+) 1346 WP_420031098.1 IS3 family transposase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29232.17 Da        Isoelectric Point: 4.1347

>NTDB_id=1127364 FGK96_RS08080 WP_138082942.1 1676821..1677576(-) (mecA) [Streptococcus porcinus strain NCTC10710]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKEIDFEDLTDLGDVSQMTPEDFFKTIEKNMIEKGDVNAHEKLEKIEEMLEEAVEASQSQTTVADESAQIVEPMDYVHYV
FDFLTIEEVISFSKIVNFPIEASELYKETSRYHLTILLDIQNQPAYFANIMYARLIEHALPGSKTRAYLQEHATLLIEDQ
AIEQLKRIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1127364 FGK96_RS08080 WP_138082942.1 1676821..1677576(-) (mecA) [Streptococcus porcinus strain NCTC10710]
ATGGAAATGAAACAAATTAGTGAAACAACACTAAAAATAACGATCAGCATGGATGATTTAGAAGAAAGGGGAATGGAATT
AAAAGATTTCTTGATTCCTCAGGAAAAAACAGAAGAATTCTTCTATACCGTTATGGATGAGTTGGATTTACCTGAAAACT
TTAAAGATAGTGGGATGTTGAGTTTTAGAGTTACCCCACGTAAAGATCGTTTAGATGTTTTTGTTACTAAGTCAGAATTA
TCTAAAGAAATTGATTTTGAAGATTTAACTGATTTAGGAGATGTTTCTCAGATGACACCCGAAGATTTTTTTAAAACAAT
TGAAAAAAACATGATAGAAAAAGGTGATGTCAATGCCCATGAAAAATTGGAAAAAATTGAAGAAATGTTAGAAGAAGCAG
TCGAGGCAAGCCAATCTCAAACTACAGTGGCTGATGAATCTGCCCAGATTGTTGAACCAATGGACTACGTTCATTATGTT
TTTGATTTTTTAACTATAGAGGAAGTCATCAGTTTTTCTAAAATAGTTAACTTTCCAATTGAAGCTTCAGAGCTTTACAA
GGAAACTAGTCGTTACCATCTAACAATCTTACTTGATATTCAAAATCAGCCAGCCTACTTTGCTAATATTATGTATGCTA
GGTTAATTGAACATGCACTACCTGGTTCAAAAACACGTGCTTATTTGCAAGAGCATGCAACCTTACTCATTGAAGATCAG
GCAATAGAGCAGTTGAAAAGGATTGAATTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9ZJX0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

61.694

98.805

0.61
  mecA Streptococcus thermophilus LMD-9

57.085

98.406

0.562
  mecA Streptococcus thermophilus LMG 18311

56.68

98.406

0.558
  mecA Streptococcus pneumoniae TIGR4

45.02

100

0.45
  mecA Streptococcus pneumoniae Rx1

44.622

100

0.446
  mecA Streptococcus pneumoniae D39

44.622

100

0.446
  mecA Streptococcus pneumoniae R6

44.622

100

0.446

Multiple sequence alignment